Anti-PPP1R7 Antibody (CAB13041)
- SKU:
- CAB13041
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-PPP1R7 Antibody |
| Antibody SKU: | CAB13041 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 281-360 of human PPP1R7 (NP_002703.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | 293T, SGC-7901, Mouse liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 281-360 of human PPP1R7 (NP_002703.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | IASN RIKK IENI SHLT ELQE FWMN DNLL ESWS DLDE LKGA RSLE TVYL ERNP LQKD PQYR RKVM LALP SVRQ IDAT FVRF |
| Gene ID: | 5510 |
| Uniprot: | Q15435 |
| Cellular Location: | Nucleus |
| Calculated MW: | 25kDa/27kDa/32kDa/36kDa/41kDa |
| Observed MW: | 39kDa |
| Synonyms: | PPP1R7, SDS22 |
| Background: | This gene encodes a protein subunit that regulates the activity of the serine/threonine phosphatase, protein phosphatase-1. The encoded protein is required for completion of the mitotic cycle and for targeting protein phosphatase-1 to mitotic kinetochores. Alternate splicing results in multiple transcript variants. |
| UniProt Protein Function: | PPP1R7: Regulatory subunit of protein phosphatase 1. Belongs to the SDS22 family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Protein phosphatase, regulatory subunit; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 2q37.3 Cellular Component: chromosome; cytoplasm; nucleus Molecular Function:protein binding; protein phosphatase type 1 regulator activity Biological Process: positive regulation of protein amino acid dephosphorylation |
| NCBI Summary: | This gene encodes a protein subunit that regulates the activity of the serine/threonine phosphatase, protein phosphatase-1. The encoded protein is required for completion of the mitotic cycle and for targeting protein phosphatase-1 to mitotic kinetochores. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] |
| UniProt Code: | Q15435 |
| NCBI GenInfo Identifier: | 74762145 |
| NCBI Gene ID: | 5510 |
| NCBI Accession: | Q15435.1 |
| UniProt Secondary Accession: | Q15435,Q9UQE5, Q9UQE6, Q9Y6K4, B4DFD4, B5MCY6, |
| UniProt Related Accession: | Q15435 |
| Molecular Weight: | 25,593 Da |
| NCBI Full Name: | Protein phosphatase 1 regulatory subunit 7 |
| NCBI Synonym Full Names: | protein phosphatase 1 regulatory subunit 7 |
| NCBI Official Symbol: | PPP1R7 |
| NCBI Official Synonym Symbols: | SDS22 |
| NCBI Protein Information: | protein phosphatase 1 regulatory subunit 7 |
| UniProt Protein Name: | Protein phosphatase 1 regulatory subunit 7 |
| UniProt Synonym Protein Names: | Protein phosphatase 1 regulatory subunit 22 |
| Protein Family: | Protein phosphatase 1 regulatory |
| UniProt Gene Name: | PPP1R7 |
| UniProt Entry Name: | PP1R7_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PPP1R7 antibody (CAB13041) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |