Anti-PPIC Antibody (CAB9837)
- SKU:
- CAB9837
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-PPIC Antibody |
| Antibody SKU: | CAB9837 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-212 of human PPIC (NP_000934.1). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| Reactivity: | Human |
| Positive Samples: | HeLa, MCF7, SW480, HepG2 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 23-212 of human PPIC (NP_000934.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | SSGA EGFR KRGP SVTA KVFF DVRI GDKD VGRI VIGL FGKV VPKT VENF VALA TGEK GYGY KGSK FHRV IKDF MIQG GDIT TGDG TGGV SIYG ETFP DENF KLKH YGIG WVSM ANAG PDTN GSQF FITL TKPT WLDG KHVV FGKV IDGM TVVH SIEL QATD GHDR PLTN CSII NSGK IDVK TPFV VEIA DW |
| Gene ID: | 5480 |
| Uniprot: | P45877 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 22kDa |
| Observed MW: | 23kDa |
| Synonyms: | PPIC, CYPC |
| Background: | The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase)) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. Similar to other PPIases, this protein can bind immunosuppressant cyclosporin A. |
| UniProt Protein Function: | PPIC: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Belongs to the cyclophilin-type PPIase family. |
| UniProt Protein Details: | Protein type:EC 5.2.1.8; Isomerase; Cyclophilin Chromosomal Location of Human Ortholog: 5q23.2 Molecular Function:cyclosporin A binding; peptidyl-prolyl cis-trans isomerase activity; protein binding |
| NCBI Summary: | The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase)) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. Similar to other PPIases, this protein can bind immunosuppressant cyclosporin A. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P45877 |
| NCBI GenInfo Identifier: | 1169178 |
| NCBI Gene ID: | 5480 |
| NCBI Accession: | P45877.1 |
| UniProt Secondary Accession: | P45877,A4LBB5, |
| UniProt Related Accession: | P45877 |
| Molecular Weight: | 22,763 Da |
| NCBI Full Name: | Peptidyl-prolyl cis-trans isomerase C |
| NCBI Synonym Full Names: | peptidylprolyl isomerase C |
| NCBI Official Symbol: | PPIC |
| NCBI Official Synonym Symbols: | CYPC |
| NCBI Protein Information: | peptidyl-prolyl cis-trans isomerase C |
| UniProt Protein Name: | Peptidyl-prolyl cis-trans isomerase C |
| UniProt Synonym Protein Names: | Cyclophilin C; Rotamase C |
| Protein Family: | Peptidyl-prolyl cis-trans isomerase |
| UniProt Gene Name: | PPIC |
| UniProt Entry Name: | PPIC_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PPIC antibody (CAB9837) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
 | Immunohistochemistry of paraffin-embedded human prostate using PPIC antibody (CAB9837) at dilution of 1:100 (40x lens). |
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