Anti-POGLUT1 Antibody (CAB17737)
- SKU:
- CAB17737
- Product type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| Antibody Name: | Anti-POGLUT1 Antibody |
| Antibody SKU: | CAB17737 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 160-280 of human POGLUT1 (NP_689518.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse spleen, Mouse lung, Mouse brain, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 160-280 of human POGLUT1 (NP_689518.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MYPA WTFW EGGP AVWP IYPT GLGR WDLF REDL VRSA AQWP WKKK NSTA YFRG SRTS PERD PLIL LSRK NPKL VDAE YTKN QAWK SMKD TLGK PAAK DVHL VDHC KYKY LFNF RGVA ASFR F |
| Gene ID: | 56983 |
| Uniprot: | Q8NBL1 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 46kDa |
 | Western blot - POGLUT1 Polyclonal Antibody (CAB17737) |
| Synonyms: | C3orf9, CLP46, KDELCL1, KTELC1, LGMD2Z, MDS010, MDSRP, Rumi, hCLP46, POGLUT1 |
| Background: | This gene encodes a protein with both O-glucosyltransferase and O-xylosyltransferase activity which localizes to the lumen of the endoplasmic reticulum. This protein has a carboxy-terminal KTEL motif which is predicted to function as an endoplasmic reticulum retention signal. This gene is an essential regulator of Notch signalling and likely plays a role in cell fate and tissue formation during development. It may also play a role in the pathogenesis of leukemia. Mutations in this gene have been associated with the autosomal dominant genodermatosis Dowling-Degos disease 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] |
| UniProt Protein Function: | KTELC1: UDP-glucosyltransferase. Belongs to the glycosyltransferase 90 family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide; EC 2.4.2.26 Chromosomal Location of Human Ortholog: 3q13.33 Cellular Component: endoplasmic reticulum lumen Molecular Function:glucosyltransferase activity; UDP-glucosyltransferase activity; UDP-xylosyltransferase activity Biological Process: glycolipid metabolic process; positive regulation of Notch signaling pathway; protein amino acid O-linked glycosylation Disease: Dowling-degos Disease 4 |
| NCBI Summary: | This gene encodes a protein with both O-glucosyltransferase and O-xylosyltransferase activity which localizes to the lumen of the endoplasmic reticulum. This protein has a carboxy-terminal KTEL motif which is predicted to function as an endoplasmic reticulum retention signal. This gene is an essential regulator of Notch signalling and likely plays a role in cell fate and tissue formation during development. It may also play a role in the pathogenesis of leukemia. Mutations in this gene have been associated with the autosomal dominant genodermatosis Dowling-Degos disease 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] |
| UniProt Code: | Q8NBL1 |
| NCBI GenInfo Identifier: | 74730148 |
| NCBI Gene ID: | 56983 |
| NCBI Accession: | Q8NBL1.1 |
| UniProt Secondary Accession: | Q8NBL1,Q53GJ4, Q8N2T1, B2RD13, |
| UniProt Related Accession: | Q8NBL1 |
| Molecular Weight: | 46,189 Da |
| NCBI Full Name: | Protein O-glucosyltransferase 1 |
| NCBI Synonym Full Names: | protein O-glucosyltransferase 1 |
| NCBI Official Symbol: | POGLUT1 |
| NCBI Official Synonym Symbols: | Rumi; CLP46; MDSRP; C3orf9; KTELC1; MDS010; hCLP46; KDELCL1 |
| NCBI Protein Information: | protein O-glucosyltransferase 1 |
| UniProt Protein Name: | Protein O-glucosyltransferase 1 |
| UniProt Synonym Protein Names: | CAP10-like 46 kDa protein; hCLP46; KTEL motif-containing protein 1; Myelodysplastic syndromes relative protein; O-glucosyltransferase Rumi homolog; hRumi; Protein O-xylosyltransferase (EC:2.4.2.26) |
| Protein Family: | Protein O-glucosyltransferase |
| UniProt Gene Name: | POGLUT1 |
| UniProt Entry Name: | PGLT1_HUMAN |
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
Anti-WBP1 Antibody (CAB13212)
