Anti-POF1B Antibody (CAB17775)

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SKU:
CAB17775
Product type:
Antibody
Reactivity:
Human
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Frequently bought together:

Description

system_update_alt데이터시트system_update_alt안전 데이터시트
Antibody Name:Anti-POF1B Antibody
Antibody SKU:CAB17775
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 330-560 of human POF1B (NP_079197.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Rat
Positive Samples:Rat kidney
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 330-560 of human POF1B (NP_079197.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:LVLS TFSN IREE LGHL QNDM TSLE NDKM RLEK DLSF KDTQ LKEY EELL ASVR ANNH QQQQ GLQD SSSK CQAL EENN LSLR HTLS DMEY RLKE LEYC KRNL EQEN QNLR MQVS ETCT GPML QAKM DEIG NHYT EMVK NLRM EKDR EICR LRSQ LNQY HKDV SKRE GSCS DFQF KLHE LTSL LEEK DSLI KRQS EELS KLRQ EIYS SHNQ PSTG GRTT ITTK KYRT QYPI LGL
Gene ID:79983
Uniprot:Q8WVV4
Cellular Location:
Calculated MW:
Observed MW:85kDa
Anti-POF1B Antibody (CAB17775)Western blot - POF1B Polyclonal Antibody (CAB17775)
Synonyms:POF, POF2B, POF1B
Background:Premature ovarian failure (POF) is characterized by primary or secondary amenorrhea in women less than 40 years old. Two POF susceptibility regions called "POF1" and "POF2" have been identified by breakpoint mapping of X-autosome translocations. POF1 extends from Xq21-qter while POF2 extends from Xq13.3 to Xq21.1. This gene, POF1B, resides in the POF2 region. This gene is expressed at trace levels in mouse prenatal ovary and is barely detectable or absent from adult ovary, in human and in the mouse respectively. This gene's expression is restricted to epithelia with its highest expression in the epidermis, and oro-pharyngeal and gastro-intestinal tracts. The protein encoded by this gene binds non-muscle actin filaments. The role this gene may play in the etiology of premature ovarian failure remains to be determined. [provided by RefSeq, Jan 2010]
UniProt Protein Function:Plays a key role in the organization of epithelial monolayers by regulating the actin cytoskeleton. May be involved in ovary development.
NCBI Summary:Premature ovarian failure (POF) is characterized by primary or secondary amenorrhea in women less than 40 years old. Two POF susceptibility regions called "POF1" and "POF2" have been identified by breakpoint mapping of X-autosome translocations. POF1 extends from Xq21-qter while POF2 extends from Xq13.3 to Xq21.1. This gene, POF1B, resides in the POF2 region. This gene is expressed at trace levels in mouse prenatal ovary and is barely detectable or absent from adult ovary, in human and in the mouse respectively. This gene's expression is restricted to epithelia with its highest expression in the epidermis, and oro-pharyngeal and gastro-intestinal tracts. The protein encoded by this gene binds non-muscle actin filaments. The role this gene may play in the etiology of premature ovarian failure remains to be determined. [provided by RefSeq, Jan 2010]
UniProt Code:Q8WVV4
NCBI GenInfo Identifier:332278224
NCBI Gene ID:79983
NCBI Accession:Q8WVV4.3
UniProt Secondary Accession:Q8WVV4,Q5H9E9, Q5H9F0, Q8NG12, Q9H5Y2, Q9H738, Q9H744 A8K2U5,
UniProt Related Accession:Q8WVV4
Molecular Weight:34,841 Da
NCBI Full Name:Protein POF1B
NCBI Synonym Full Names:premature ovarian failure, 1B
NCBI Official Symbol:POF1B  
NCBI Official Synonym Symbols:POF; POF2B  
NCBI Protein Information:protein POF1B
UniProt Protein Name:Protein POF1B
UniProt Synonym Protein Names:Premature ovarian failure protein 1B
Protein Family:Protein
UniProt Gene Name:POF1B  
UniProt Entry Name:POF1B_HUMAN

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