Anti-Plexin A1 Antibody (CAB3698)
- SKU:
- CAB3698
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- NOV
- NOVP
- PLEXIN-A1
- PLXN1
Frequently bought together:
Description
| Product Name: | Plexin A1 Rabbit mAb |
| Product Code: | CAB3698 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | NOV, NOVP, PLEXIN-A1, PLXN1 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Plexin A1 |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | K-562, Mouse brain, Rat testis |
| Immunogen: | A synthesized peptide derived from human Plexin A1 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 5361 |
| Uniprot: | Q9UIW2 |
| Calculated MW: | 211kDa |
| Observed MW: | 250kDa |
| UniProt Protein Function: | PLXNA1: Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down- stream signaling events in the cytoplasm. Interacts directly with NRP1 and NRP2. Interacts with FARP2, RND1 and KDR/VEGFR2. Binding of SEMA3A leads to dissociation of FARP2. Detected in fetal brain, lung, liver and kidney. Belongs to the plexin family. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Receptor, misc.; Membrane protein, integral Chromosomal Location of Human Ortholog: 3q21.3 Cellular Component: cytoplasm; integral to membrane; plasma membrane; nucleus Molecular Function:semaphorin receptor activity; receptor activity Biological Process: axon guidance; regulation of smooth muscle cell migration; multicellular organismal development |
| UniProt Code: | Q9UIW2 |
| NCBI GenInfo Identifier: | 313104202 |
| NCBI Gene ID: | 5361 |
| NCBI Accession: | Q9UIW2.3 |
| UniProt Related Accession: | Q9UIW2 |
| Molecular Weight: | 211,067 Da |
| NCBI Full Name: | Plexin-A1 |
| NCBI Synonym Full Names: | plexin A1 |
| NCBI Official Symbol: | PLXNA1 |
| NCBI Official Synonym Symbols: | NOV; NOVP; PLXN1; PLEXIN-A1 |
| NCBI Protein Information: | plexin-A1; plexin 1; semaphorin receptor NOV |
| UniProt Protein Name: | Plexin-A1 |
| UniProt Synonym Protein Names: | Semaphorin receptor NOV |
| Protein Family: | Plexin |
| UniProt Gene Name: | PLXNA1 |
| UniProt Entry Name: | PLXA1_HUMAN |
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