Anti-PLEK2 Antibody (CAB17682)

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SKU:
CAB17682
Product type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Frequently bought together:

Description

system_update_alt데이터시트system_update_alt안전 데이터시트
Antibody Name:Anti-PLEK2 Antibody
Antibody SKU:CAB17682
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human PLEK2 (NP_057529.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:Mouse stomach, Mouse thymus
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human PLEK2 (NP_057529.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MEDG VLKE GFLV KRGH IVHN WKAR WFIL RQNT LVYY KLEG GRRV TPPK GRIL LDGC TITC PCLE YENR PLLI KLKT QTST EYFL EACS REER DAWA FEIT GAIH AGQP GKVQ QLHS LRNS FKLP PHIS LHRI VDKM HDSN TGIR SSPN MEQG STYK KTFL GSSL VDWL ISNS FTAS RLEA VTLA SMLM EENF LRPV GVRS MGAI RSGD LAEQ FLDD STAL YTFA ESYK KKIS PKEE ISLS TVEL SGTV VK
Gene ID:26499
Uniprot:Q9NYT0
Cellular Location:
Calculated MW:39kDa
Observed MW:40kDa
Anti-PLEK2 Antibody (CAB17682)Western blot - PLEK2 Polyclonal Antibody (CAB17682)
Synonyms:PLEK2
Background:The protein encoded by this gene associates with membrane-bound phosphatidylinositols generated by phosphatidylinositol 3-kinase. The encoded protein then interacts with the actin cytoskeleton to induce cell spreading. In conjunction with complement component 1, q subcomponent, B chain (C1QB), this gene shows an increase in expression in melanoma cells and may serve as an accurate biomarker for the disease. [provided by RefSeq, Dec 2015]
UniProt Protein Function:PLEK2: May help orchestrate cytoskeletal arrangement. Contribute to lamellipodia formation.
UniProt Protein Details:

Protein type:Cytoskeletal

Chromosomal Location of Human Ortholog: 14q23.3-q24.1

Cellular Component: cytoplasm; cytoskeleton

Molecular Function:phosphatidylinositol-3,4-bisphosphate binding

Biological Process: actin cytoskeleton organization; positive regulation of cell projection organization

NCBI Summary:The protein encoded by this gene associates with membrane-bound phosphatidylinositols generated by phosphatidylinositol 3-kinase. The encoded protein then interacts with the actin cytoskeleton to induce cell spreading. In conjunction with complement component 1, q subcomponent, B chain (C1QB), this gene shows an increase in expression in melanoma cells and may serve as an accurate biomarker for the disease. [provided by RefSeq, Dec 2015]
UniProt Code:Q9NYT0
NCBI GenInfo Identifier:7706643
NCBI Gene ID:26499
NCBI Accession:NP_057529.1
UniProt Secondary Accession:Q9NYT0,Q96JT0,
UniProt Related Accession:Q9NYT0
Molecular Weight:39,971 Da
NCBI Full Name:pleckstrin-2
NCBI Synonym Full Names:pleckstrin 2
NCBI Official Symbol:PLEK2  
NCBI Protein Information:pleckstrin-2
UniProt Protein Name:Pleckstrin-2
Protein Family:Pleckstrin
UniProt Gene Name:PLEK2  

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