Anti-PLD2 Antibody (CAB10192)
- SKU:
- CAB10192
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
| Antibody Name: | Anti-PLD2 Antibody |
| Antibody SKU: | CAB10192 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human PLD2 (NP_002654.3). |
| Application: | WB |
| Recommended Dilution: | WB 1:1000 - 1:3000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | B-cell, HeLa, U-87MG, BT-474, A375 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human PLD2 (NP_002654.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MTAT PESL FPTG DELD SSQL QMES DEVD TLKE GEDP ADRM HPFL AIYE LQSL KVHP LVFA PGVP VTAQ VVGT ERYT SGSK VGTC TLYS VRLT HGDF SWTT KKKY RHFQ ELHR DLLR HKVL MSLL PLAR FAVA YSPA RDAG NREM PSLP RAGP EGST RHAA SKQK YLEN YLNR LLTM SFYR |
| Gene ID: | 5338 |
| Uniprot: | O14939 |
| Cellular Location: | Membrane, Peripheral membrane protein |
| Calculated MW: | 38kDa/104kDa/105kDa |
| Observed MW: | 110kDa |
| Synonyms: | PLD2, PLD1C |
| Background: | The protein encoded by this gene catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4, 5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and/or regulated secretion. Two transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | May have a role in signal-induced cytoskeletal regulation and/or endocytosis. |
| NCBI Summary: | The protein encoded by this gene catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4,5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and/or regulated secretion. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011] |
| UniProt Code: | O14939 |
| NCBI GenInfo Identifier: | 13124441 |
| NCBI Gene ID: | 5338 |
| NCBI Accession: | O14939.2 |
| UniProt Secondary Accession: | O14939,O43540, O43579, O43580, Q6PGR0, Q96BY3, I3L2C9 |
| UniProt Related Accession: | O14939 |
| Molecular Weight: | 104,657 Da |
| NCBI Full Name: | Phospholipase D2 |
| NCBI Synonym Full Names: | phospholipase D2 |
| NCBI Official Symbol: | PLD2 |
| NCBI Official Synonym Symbols: | PLD1C |
| NCBI Protein Information: | phospholipase D2 |
| UniProt Protein Name: | Phospholipase D2 |
| UniProt Synonym Protein Names: | Choline phosphatase 2; PLD1C; Phosphatidylcholine-hydrolyzing phospholipase D2 |
| Protein Family: | Phospholipase |
| UniProt Gene Name: | PLD2 |
 | Western blot analysis of extracts of various cell lines, using PLD2 antibody (CAB10192) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
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