Anti-PIM2 Antibody (CAB9230)
- SKU:
- CAB9230
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Death
Description
Antibody Name: | Anti-PIM2 Antibody |
Antibody SKU: | CAB9230 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human |
Host Species: | Rabbit |
Immunogen: | A synthesized peptide derived from human PIM2 |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human |
Positive Samples: | HepG2, K-562, Raji |
Immunogen: | A synthesized peptide derived from human PIM2 |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 11040 |
Uniprot: | Q9P1W9 |
Cellular Location: | |
Calculated MW: | 37kDa |
Observed MW: | 40KDa |
Synonyms: | |
Background: | This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival.[provided by RefSeq, Nov 2009] |
UniProt Protein Function: | Pim2: a Ca(2 )/calmodulin-dependent protein kinase of the PIM family. Highly expressed in hematopoietic tissues, in leukemic and lymphoma cell lines, testis, small intestine, colon and colorectal adenocarcinoma cells. |
UniProt Protein Details: | Protein type:Protein kinase, CAMK; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Oncoprotein; EC 2.7.11.1; CAMK group; PIM family Chromosomal Location of Human Ortholog: Xp11.23 Cellular Component: cytoplasm Molecular Function:protein binding; protein serine/threonine kinase activity Biological Process: cell proliferation; G1/S transition of mitotic cell cycle; male meiosis; negative regulation of apoptosis; negative regulation of cell proliferation; positive regulation of autophagy; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of transcription, DNA-dependent; protein amino acid autophosphorylation; protein amino acid phosphorylation; protein stabilization; regulation of mitotic cell cycle; response to virus |
NCBI Summary: | This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival.[provided by RefSeq, Nov 2009] |
UniProt Code: | Q9P1W9 |
NCBI GenInfo Identifier: | 20139243 |
NCBI Gene ID: | 11040 |
NCBI Accession: | Q9P1W9.1 |
UniProt Secondary Accession: | Q9P1W9,Q99739, A8K4G6, |
UniProt Related Accession: | Q9P1W9 |
Molecular Weight: | 34,190 Da |
NCBI Full Name: | Serine/threonine-protein kinase pim-2 |
NCBI Synonym Full Names: | Pim-2 proto-oncogene, serine/threonine kinase |
NCBI Official Symbol: | PIM2 |
NCBI Protein Information: | serine/threonine-protein kinase pim-2 |
UniProt Protein Name: | Serine/threonine-protein kinase pim-2 |
UniProt Synonym Protein Names: | Pim-2h |
Protein Family: | Serine/threonine-protein kinase |
UniProt Gene Name: | PIM2 |
UniProt Entry Name: | PIM2_HUMAN |