Anti-PIM2 Antibody (CAB15598)
- SKU:
- CAB15598
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Description
| Antibody Name: | Anti-PIM2 Antibody |
| Antibody SKU: | CAB15598 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human PIM2 (NP_006866.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | Raji, Jurkat, HeLa, Mouse brain |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human PIM2 (NP_006866.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | TRVY SPPE WISR HQYH ALPA TVWS LGIL LYDM VCGD IPFE RDQE ILEA ELHF PAHV SPDC CALI RRCL APKP SSRP SLEE ILLD PWMQ TPAE DVPL NPSK GGPA PLAW SLLP |
| Gene ID: | 11040 |
| Uniprot: | Q9P1W9 |
| Cellular Location: | |
| Calculated MW: | 34kDa |
| Observed MW: | 38kDa |
| Synonyms: | PIM2 |
| Background: | This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival. |
| UniProt Protein Function: | Pim2: a Ca(2 )/calmodulin-dependent protein kinase of the PIM family. Highly expressed in hematopoietic tissues, in leukemic and lymphoma cell lines, testis, small intestine, colon and colorectal adenocarcinoma cells. |
| UniProt Protein Details: | Protein type:Protein kinase, CAMK; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Oncoprotein; EC 2.7.11.1; CAMK group; PIM family Chromosomal Location of Human Ortholog: Xp11.23 Cellular Component: cytoplasm Molecular Function:protein binding; protein serine/threonine kinase activity Biological Process: cell proliferation; G1/S transition of mitotic cell cycle; male meiosis; negative regulation of apoptosis; negative regulation of cell proliferation; positive regulation of autophagy; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of transcription, DNA-dependent; protein amino acid autophosphorylation; protein amino acid phosphorylation; protein stabilization; regulation of mitotic cell cycle; response to virus |
| NCBI Summary: | This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival.[provided by RefSeq, Nov 2009] |
| UniProt Code: | Q9P1W9 |
| NCBI GenInfo Identifier: | 20139243 |
| NCBI Gene ID: | 11040 |
| NCBI Accession: | Q9P1W9.1 |
| UniProt Secondary Accession: | Q9P1W9,Q99739, A8K4G6, |
| UniProt Related Accession: | Q9P1W9 |
| Molecular Weight: | 34,190 Da |
| NCBI Full Name: | Serine/threonine-protein kinase pim-2 |
| NCBI Synonym Full Names: | Pim-2 proto-oncogene, serine/threonine kinase |
| NCBI Official Symbol: | PIM2 |
| NCBI Protein Information: | serine/threonine-protein kinase pim-2 |
| UniProt Protein Name: | Serine/threonine-protein kinase pim-2 |
| UniProt Synonym Protein Names: | Pim-2h |
| Protein Family: | Serine/threonine-protein kinase |
| UniProt Gene Name: | PIM2 |
| UniProt Entry Name: | PIM2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PIM2 antibody (CAB15598) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
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