Anti-PIGO Antibody (CAB18670)
- SKU:
- CAB18670
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| Antibody Name: | Anti-PIGO Antibody |
| Antibody SKU: | CAB18670 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human PIGO. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | HeLa, 22Rv1, Mouse uterus, Mouse spleen |
| Immunogen: | Recombinant protein of human PIGO. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 84720 |
| Uniprot: | Q8TEQ8 |
| Cellular Location: | Endoplasmic reticulum membrane, Multi-pass membrane protein |
| Calculated MW: | 73kDa/118kDa |
| Observed MW: | 119kDa |
 | Western blot - PIGO Rabbit pAb (CAB18670) |
| Synonyms: | PIGO, HPMRS2, GPI ethanolamine phosphate transferase 3 |
| Background: | This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This protein is involved in the transfer of ethanolaminephosphate (EtNP) to the third mannose in GPI. At least three alternatively spliced transcripts encoding two distinct isoforms have been found for this gene. |
| UniProt Protein Function: | PIGO: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI-anchor to the C-terminus of the proteins by an amide bond. Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Transferase; Membrane protein, multi-pass; Endoplasmic reticulum; Membrane protein, integral; EC 2.-.-.- Chromosomal Location of Human Ortholog: 9p13.3 Cellular Component: endoplasmic reticulum membrane; membrane Molecular Function:mannose-ethanolamine phosphotransferase activity Biological Process: GPI anchor biosynthetic process Disease: Hyperphosphatasia With Mental Retardation Syndrome 2 |
| NCBI Summary: | This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This protein is involved in the transfer of ethanolaminephosphate (EtNP) to the third mannose in GPI. At least three alternatively spliced transcripts encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2011] |
| UniProt Code: | Q8TEQ8 |
| NCBI GenInfo Identifier: | 61252289 |
| NCBI Gene ID: | 84720 |
| NCBI Accession: | Q8TEQ8.3 |
| UniProt Secondary Accession: | Q8TEQ8,Q6P154, Q6UX80, Q8TDS8, Q96CS9, Q9BVN9, Q9Y4B0 B1AML3, |
| UniProt Related Accession: | Q8TEQ8 |
| Molecular Weight: | 73,992 Da |
| NCBI Full Name: | GPI ethanolamine phosphate transferase 3 |
| NCBI Synonym Full Names: | phosphatidylinositol glycan anchor biosynthesis class O |
| NCBI Official Symbol: | PIGO |
| NCBI Official Synonym Symbols: | HPMRS2 |
| NCBI Protein Information: | GPI ethanolamine phosphate transferase 3 |
| UniProt Protein Name: | GPI ethanolamine phosphate transferase 3 |
| UniProt Synonym Protein Names: | Phosphatidylinositol-glycan biosynthesis class O protein; PIG-O |
| UniProt Gene Name: | PIGO |
| UniProt Entry Name: | PIGO_HUMAN |
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