Anti-PI 3 Kinase p55 gamma Antibody (CAB3980)
- SKU:
- CAB3980
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-PI 3 Kinase p55 gamma Antibody |
| Antibody SKU: | CAB3980 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human PI 3 Kinase p55 gamma |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | PC-3, Raji, SH-SY5Y, Mouse testis, Mouse brain, Rat testis, Rat brain |
| Immunogen: | A synthesized peptide derived from human PI 3 Kinase p55 gamma |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 8503 |
| Uniprot: | Q92569 |
| Cellular Location: | |
| Calculated MW: | 54kDa |
| Observed MW: | 52KDa |
| Synonyms: | p55, p55-GAMMA, p55PIK |
| Background: | Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and a regulatory subunit. The protein encoded by this gene represents a regulatory subunit of PI3K. The encoded protein contains two SH2 domains through which it binds activated protein tyrosine kinases to regulate their activity. [provided by RefSeq, Jun 2016] |
| UniProt Protein Function: | PIK3R3: Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1. Heterodimer of a regulatory subunit PIK3R3 and a p110 catalytic subunit (PIK3CA, PIK3CB or PIK3CD). Interacts with AXL. Highest levels in brain and testis. Lower levels in adipose tissue, kidney, heart, lung and skeletal muscle. Belongs to the PI3K p85 subunit family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Kinase, lipid Chromosomal Location of Human Ortholog: 1p34.1 Cellular Component: cytosol; phosphoinositide 3-kinase complex Molecular Function:protein binding; 1-phosphatidylinositol-3-kinase activity; phosphoinositide 3-kinase regulator activity Biological Process: phospholipid metabolic process; phosphatidylinositol biosynthetic process; insulin receptor signaling pathway; regulation of phosphoinositide 3-kinase activity |
| NCBI Summary: | Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and a regulatory subunit. The protein encoded by this gene represents a regulatory subunit of PI3K. The encoded protein contains two SH2 domains through which it binds activated protein tyrosine kinases to regulate their activity. [provided by RefSeq, Jun 2016] |
| UniProt Code: | Q92569 |
| NCBI GenInfo Identifier: | 317373310 |
| NCBI Gene ID: | 8503 |
| NCBI Accession: | Q92569.2 |
| UniProt Related Accession: | Q92569 |
| Molecular Weight: | |
| NCBI Full Name: | Phosphatidylinositol 3-kinase regulatory subunit gamma |
| NCBI Synonym Full Names: | phosphoinositide-3-kinase regulatory subunit 3 |
| NCBI Official Symbol: | PIK3R3 |
| NCBI Official Synonym Symbols: | p55; p55PIK; p55-GAMMA |
| NCBI Protein Information: | phosphatidylinositol 3-kinase regulatory subunit gamma |
| UniProt Protein Name: | Phosphatidylinositol 3-kinase regulatory subunit gamma |
| UniProt Synonym Protein Names: | Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma; PI3-kinase subunit p55-gamma; PtdIns-3-kinase regulatory subunit p55-gamma; p55PIK |
| UniProt Gene Name: | PIK3R3 |
| UniProt Entry Name: | P55G_HUMAN |
 | Western blot - PI 3 Kinase p55 gamma Rabbit mAb (CAB3980) |
Related Products
Anti-PI 3 Kinase Class 3 Antibody (CAB12295)
Anti-14-3-3 gamma Antibody (CAB9162)
Anti-PPAR gamma Antibody (CAB11183)
