Anti-PGAM2 Antibody (CAB7917)
- SKU:
- CAB7917
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
| Antibody Name: | Anti-PGAM2 Antibody |
| Antibody SKU: | CAB7917 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-253 of human PGAM2 (NP_000281.2). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 22Rv1, SH-SY5Y, U-87MG, Mouse kidney, Mouse testis, Mouse skeletal muscle, Rat brain, Rat kidney, Rat skeletal muscle |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-253 of human PGAM2 (NP_000281.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MATH RLVM VRHG ESTW NQEN RFCG WFDA ELSE KGTE EAKR GAKA IKDA KMEF DICY TSVL KRAI RTLW AILD GTDQ MWLP VVRT WRLN ERHY GGLT GLNK AETA AKHG EEQV KIWR RSFD IPPP PMDE KHPY YNSI SKER RYAG LKPG ELPT CESL KDTI ARAL PFWN EEIV PQIK AGKR VLIA AHGN SLRG IVKH LEGM SDQA IMEL NLPT GIPI VYEL NKEL KPTK PMQF LGDE ETVR KAME AVAA QGKA K |
| Gene ID: | 5224 |
| Uniprot: | P15259 |
| Cellular Location: | |
| Calculated MW: | 28kDa |
| Observed MW: | 29kDa |
| Synonyms: | PGAM2, GSD10, PGAM-M, PGAMM |
| Background: | Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). This gene encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X. |
| UniProt Code: | P15259 |
| NCBI GenInfo Identifier: | 50593010 |
| NCBI Gene ID: | 5224 |
| NCBI Accession: | NP_000281.2 |
| UniProt Related Accession: | P15259 |
| Molecular Weight: | 28,766 Da |
| NCBI Full Name: | phosphoglycerate mutase 2 |
| NCBI Synonym Full Names: | phosphoglycerate mutase 2 |
| NCBI Official Symbol: | PGAM2 |
| NCBI Official Synonym Symbols: | GSD10; PGAMM; PGAM-M |
| NCBI Protein Information: | phosphoglycerate mutase 2 |
| UniProt Protein Name: | Phosphoglycerate mutase 2 |
| UniProt Synonym Protein Names: | BPG-dependent PGAM 2; Muscle-specific phosphoglycerate mutase; Phosphoglycerate mutase isozyme M; PGAM-M |
| Protein Family: | Phosphoglycerate mutase |
| UniProt Gene Name: | PGAM2 |
 | Western blot analysis of extracts of various cell lines, using PGAM2 antibody (CAB7917) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 15s. |
 | Immunofluorescence analysis of rat heart using PGAM2 Rabbit pAb (CAB7917) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. |
 | Immunofluorescence analysis of mouse heart using PGAM2 Rabbit pAb (CAB7917) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining. |
Related Products
Rat Phosphoglycerate mutase 2 / PGAM2 ELISA Kit
Human Phosphoglycerate mutase 2 (PGAM2) ELISA Kit
