Anti-PGAM1 Antibody (CAB4170)
- SKU:
- CAB4170
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
| Antibody Name: | Anti-PGAM1 Antibody |
| Antibody SKU: | CAB4170 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human PGAM1 |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, HepG2, U-251MG, Mouse liver, Mouse brain, Mouse kidney, Rat brain, Rat spleen, Rat kidney |
| Immunogen: | A synthesized peptide derived from human PGAM1 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 5223 |
| Uniprot: | P18669 |
| Cellular Location: | |
| Calculated MW: | 29kDa |
| Observed MW: | 28KDa |
| Synonyms: | HEL-S-35, PGAM-B, PGAMA |
| Background: | The protein encoded by this gene is a mutase that catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015] |
| UniProt Protein Function: | PGAM1: Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity. Homodimer. In mammalian tissues there are two types of phosphoglycerate mutase isozymes: type-M in muscles and type-B in other tissues. Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. |
| UniProt Protein Details: | Protein type:EC 5.4.2.4; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Isomerase; EC 3.1.3.13; Phosphatase (non-protein); EC 5.4.2.11 Chromosomal Location of Human Ortholog: 10q25.3 Cellular Component: membrane; cytoplasm; cytosol Molecular Function:protein binding; phosphoglycerate mutase activity; bisphosphoglycerate mutase activity; bisphosphoglycerate phosphatase activity; protein kinase binding Biological Process: respiratory burst; glycolysis; dephosphorylation; regulation of glycolysis; carbohydrate metabolic process; glucose metabolic process; pathogenesis; regulation of pentose-phosphate shunt; gluconeogenesis |
| NCBI Summary: | Phosphoglyceric acid mutase (EC 2.7.5.3) is widely distributed in mammalian tissues where it catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway (summary by Chen et al., 1974 [PubMed 4811757]).[supplied by OMIM, Nov 2010] |
| UniProt Code: | P18669 |
| NCBI GenInfo Identifier: | 130348 |
| NCBI Gene ID: | 5223 |
| NCBI Accession: | P18669.2 |
| UniProt Secondary Accession: | P18669,Q9BWC0, |
| UniProt Related Accession: | P18669 |
| Molecular Weight: | 254 |
| NCBI Full Name: | Phosphoglycerate mutase 1 |
| NCBI Synonym Full Names: | phosphoglycerate mutase 1 (brain) |
| NCBI Official Symbol: | PGAM1 |
| NCBI Official Synonym Symbols: | PGAMA; PGAM-B; HEL-S-35 |
| NCBI Protein Information: | phosphoglycerate mutase 1; BPG-dependent PGAM 1; phosphoglycerate mutase isozyme B; epididymis secretory protein Li 35; phosphoglycerate mutase A, nonmuscle form |
| UniProt Protein Name: | Phosphoglycerate mutase 1 |
| UniProt Synonym Protein Names: | BPG-dependent PGAM 1; Phosphoglycerate mutase isozyme B; PGAM-B |
| Protein Family: | Phosphoglycerate mutase |
| UniProt Gene Name: | PGAM1 |
| UniProt Entry Name: | PGAM1_HUMAN |
 | Western blot - PGAM1 Rabbit mAb (CAB4170) |
Related Products
Human PGAM1 / Phosphoglycerate Mutase 1 ELISA Kit
