Anti-Peroxiredoxin 4 Antibody (CAB9131)
- SKU:
- CAB9131
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-Peroxiredoxin 4 Antibody |
| Antibody SKU: | CAB9131 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Peroxiredoxin 4 |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Jurkat, U-251MG, Mouse liver, Rat lung |
| Immunogen: | A synthesized peptide derived from human Peroxiredoxin 4 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 10549 |
| Uniprot: | Q13162 |
| Cellular Location: | |
| Calculated MW: | 27kDa |
| Observed MW: | 27KDa |
| Synonyms: | AOE37-2, AOE372, HEL-S-97n, PRX-4 |
| Background: | The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | PRDX4: Probably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation. Belongs to the AhpC/TSA family. |
| UniProt Protein Details: | Protein type:Oxidoreductase; EC 1.11.1.15; Secreted; Mitochondrial; Secreted, signal peptide Chromosomal Location of Human Ortholog: Xp22.11 Cellular Component: cytosol; extracellular space; mitochondrion; nucleus; smooth endoplasmic reticulum Molecular Function:protein binding; protein homodimerization activity; thioredoxin peroxidase activity Biological Process: 4-hydroxyproline metabolic process; cell redox homeostasis; extracellular matrix organization and biogenesis; I-kappaB phosphorylation; male gonad development; protein maturation via protein folding; spermatogenesis |
| NCBI Summary: | The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q13162 |
| NCBI GenInfo Identifier: | 3024727 |
| NCBI Gene ID: | 10549 |
| NCBI Accession: | Q13162.1 |
| UniProt Secondary Accession: | Q13162,Q6FHT3, |
| UniProt Related Accession: | Q13162 |
| Molecular Weight: | |
| NCBI Full Name: | Peroxiredoxin-4 |
| NCBI Synonym Full Names: | peroxiredoxin 4 |
| NCBI Official Symbol: | PRDX4 |
| NCBI Official Synonym Symbols: | PRX-4; AOE372; AOE37-2; HEL-S-97n |
| NCBI Protein Information: | peroxiredoxin-4 |
| UniProt Protein Name: | Peroxiredoxin-4 |
| UniProt Synonym Protein Names: | Antioxidant enzyme AOE372; AOE37-2; Peroxiredoxin IV; Prx-IV; Thioredoxin peroxidase AO372; Thioredoxin-dependent peroxide reductase A0372 |
| Protein Family: | Peroxiredoxin |
| UniProt Gene Name: | PRDX4 |
| UniProt Entry Name: | PRDX4_HUMAN |
 | Western blot - Peroxiredoxin 4 Rabbit mAb (CAB9131) |
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