Anti-Perilipin A Antibody (CAB4758)
- SKU:
- CAB4758
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- FPLD4
- PERI
- PLIN
Frequently bought together:
Description
Product Name: | Perilipin A Rabbit mAb |
Product Code: | CAB4758 |
Size: | 20uL, 50uL, 100uL |
Synonyms: | FPLD4, PERI, PLIN |
Applications: | WB, IHC, IF |
Reactivity: | Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | A synthesized peptide derived from human Perilipin A |
Applications: | WB, IHC, IF |
Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
Reactivity: | Mouse, Rat |
Positive Samples: | Mouse testis, Mouse kidney, Mouse heart, Rat liver |
Immunogen: | A synthesized peptide derived from human Perilipin A |
Purification Method: | Affinity purification |
Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 5346 |
Uniprot: | O60240 |
Calculated MW: | 62kDa |
Observed MW: | 70KDa |
UniProt Protein Function: | perilipin 1: an adipocyte protein of the peripilin family. A modulator of adipocyte lipid metabolism, coating lipid storage droplets to protect them from being broken down by hormone-sensitive lipase. A major cAMP-dependent protein kinase-substrate in adipocytes, also dephosphorylated by PP1. When phosphorylated, may be maximally sensitive to HSL and when unphosphorylated, may play a role in the inhibition of lipolysis. |
UniProt Protein Details: | Protein type:Lipid-binding Chromosomal Location of Human Ortholog: 15q26 Cellular Component: endoplasmic reticulum; lipid particle; cytosol Molecular Function:lipid binding Biological Process: triacylglycerol catabolic process; lipid metabolic process Disease: Lipodystrophy, Familial Partial, Type 4 |
NCBI Summary: | The protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Feb 2009] |
UniProt Code: | O60240 |
NCBI GenInfo Identifier: | 229462739 |
NCBI Gene ID: | 5346 |
NCBI Accession: | O60240.2 |
UniProt Secondary Accession: | O60240,Q8N5Y6, |
UniProt Related Accession: | O60240 |
Molecular Weight: | 55,990 Da |
NCBI Full Name: | Perilipin-1 |
NCBI Synonym Full Names: | perilipin 1 |
NCBI Official Symbol: | PLIN1 |
NCBI Official Synonym Symbols: | PERI; PLIN; FPLD4 |
NCBI Protein Information: | perilipin-1; lipid droplet-associated protein |
UniProt Protein Name: | Perilipin-1 |
UniProt Synonym Protein Names: | Lipid droplet-associated protein |
Protein Family: | Perilipin |
UniProt Gene Name: | PLIN1 |
UniProt Entry Name: | PLIN1_HUMAN |