Anti-PABPC5 Antibody (CAB9997)
- SKU:
- CAB9997
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-PABPC5 Antibody |
| Antibody SKU: | CAB9997 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-382 of human PABPC5 (NP_543022.1). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:1000 - 1:4000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse |
| Positive Samples: | SH-SY5Y, A375, MCF7, Mouse liver, Mouse skeletal muscle |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-382 of human PABPC5 (NP_543022.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MGSG EPNP AGKK KKYL KAAL YVGD LDPD VTED MLYK KFRP AGPL RFTR ICRD PVTR SPLG YGYV NFRF PADA EWAL NTMN FDLI NGKP FRLM WSQP DDRL RKSG VGNI FIKN LDKS IDNR ALFY LFSA FGNI LSCK VVCD DNGS KGYA YVHF DSLA AANR AIWH MNGV RLNN RQVY VGRF KFPE ERAA EVRT RDRA TFTN VFVK NIGD DIDD EKLK ELFC EYGP TESV KVIR DASG KSKG FGFV RYET HEAA QKAV LDLH GKSI DGKV LYVG RAQK KIER LAEL RRRF ERLR LKEK SRPP GVPI YIKN LDET INDE KLKE EFSS FGSI SRAK VMME VGQG KGFG VVCF SSFE EATK AVDE MNGR IVGS KPLH VTLG QARR RC |
| Gene ID: | 140886 |
| Uniprot: | Q96DU9 |
| Cellular Location: | Cytoplasm, Mitochondrion matrix |
| Calculated MW: | 39kDa/43kDa |
| Observed MW: | 43kDa |
| Synonyms: | PABPC5, PABP5 |
| Background: | This gene encodes a protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. This gene is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder. |
| UniProt Protein Function: | PABPC5: Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. |
| UniProt Protein Details: | Protein type:RNA-binding Chromosomal Location of Human Ortholog: Xq21.3 Cellular Component: mitochondrial matrix Molecular Function:nucleotide binding; RNA binding |
| NCBI Summary: | This gene encodes a protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. This gene is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder. [provided by RefSeq, May 2010] |
| UniProt Code: | Q96DU9 |
| NCBI GenInfo Identifier: | 28201851 |
| NCBI Gene ID: | 140886 |
| NCBI Accession: | Q96DU9.1 |
| UniProt Secondary Accession: | Q96DU9,Q5JQF4, Q6P529, Q9UFE5, A8K240, |
| UniProt Related Accession: | Q96DU9 |
| Molecular Weight: | 39,941 Da |
| NCBI Full Name: | Polyadenylate-binding protein 5 |
| NCBI Synonym Full Names: | poly(A) binding protein cytoplasmic 5 |
| NCBI Official Symbol: | PABPC5 |
| NCBI Official Synonym Symbols: | PABP5 |
| NCBI Protein Information: | polyadenylate-binding protein 5 |
| UniProt Protein Name: | Polyadenylate-binding protein 5 |
| Protein Family: | Polyadenylate-binding protein |
| UniProt Gene Name: | PABPC5 |
| UniProt Entry Name: | PABP5_HUMAN |
 | Western blot analysis of extracts of various cell lines, using PABPC5 antibody (CAB9997) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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