Anti-P2Y purinoceptor 14 Antibody (CAB8178)
- SKU:
- CAB8178
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | P2RY14 Rabbit Polyclonal Antibody |
| Antibody SKU: | CAB8178 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 209-338 of human P2RY14 (NP_055694.3). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Jurkat, U-937, SH-SY5Y, MCF7, Mouse spleen, Mouse lung, Mouse heart, Rat spleen, Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 209-338 of human P2RY14 (NP_055694.3). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | ITKK IFKS HLKS SRNS TSVK KKSS RNIF SIVF VFFV CFVP YHIA RIPY TKSQ TEAH YSCQ SKEI LRYM KEFT LLLS AANV CLDP IIYF FLCQ PFRE ILCK KLHI PLKA QNDL DISR IKRG NTTL ESTD TL |
| Gene ID: | 9934 |
| Uniprot: | Q15391 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 38kDa |
| Observed MW: | 42kDa |
| Synonyms: | P2RY14, BPR105, GPR105, P2Y14 |
| Background: | The product of this gene belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene. |
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| UniProt Code: | Q15391 |
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| UniProt Secondary Accession: | Q15391 |
| UniProt Related Accession: | Q15391 |
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 | Western blot analysis of extracts of various cell lines, using P2RY14 antibody (CAB8178) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded rat ovary using P2RY14 Rabbit pAb (CAB8178) at dilution of 1:200 (40x lens). |
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