Anti-OGFR Antibody (CAB7074)
- SKU:
- CAB7074
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
| Antibody Name: | Anti-OGFR Antibody |
| Antibody SKU: | CAB7074 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human OGFR (NP_031372.2). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | A-431, Mouse kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human OGFR (NP_031372.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MDDP DCDS TWEE DEED AEDA EDED CEDG EAAG ARDA DAGD EDEE SEEP RAAR PSSF QSRM TGSR NWRA TRDM CRYR HNYP DLVE RDCN GDTP NLSF YRNE IRFL PNGC FIED ILQN WTDN YDLL EDNH SYIQ WLFP LREP GVNW HAKP LTLR EVEV FKSS QEIQ ERLV RAYE LMLG FYGI RLED RGTG TVGR AQNY QKRF QNLN WRSH NNLR ITRI LKSL GELG LEHF QAPL VRFF LEET LVRR ELPG VRQS ALDY FMFA VRCR HQRR QLVH FAWE HFRP |
| Gene ID: | 11054 |
| Uniprot: | Q9NZT2 |
| Cellular Location: | Cytoplasm, Nucleus |
| Calculated MW: | 71kDa/73kDa |
| Observed MW: | 110kDa |
| Synonyms: | OGFR |
| Background: | The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as [Met(5)]-enkephalin. OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. The coding sequence of this gene contains a polymorphic region of 60 nt tandem imperfect repeat units. Several transcripts containing between zero and eight repeat units have been reported. |
| UniProt Protein Function: | OGFR: Receptor for opioid growth factor (OGF), also known as Met-enkephalin. Seems to be involved in growth regulation. Belongs to the opioid growth factor receptor family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Receptor, misc. Chromosomal Location of Human Ortholog: 20q13.3 Cellular Component: membrane; cytoplasm; nucleus Molecular Function:opioid receptor activity Biological Process: regulation of cell growth |
| NCBI Summary: | The protein encoded by this gene is a receptor for opioid growth factor (OGF), also known as [Met(5)]-enkephalin. OGF is a negative regulator of cell proliferation and tissue organization in a variety of processes. The encoded unbound receptor for OGF has been localized to the outer nuclear envelope, where it binds OGF and is translocated into the nucleus. The coding sequence of this gene contains a polymorphic region of 60 nt tandem imperfect repeat units. Several transcripts containing between zero and eight repeat units have been reported. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9NZT2 |
| NCBI GenInfo Identifier: | 146331047 |
| NCBI Gene ID: | 11054 |
| NCBI Accession: | Q9NZT2.3 |
| UniProt Secondary Accession: | Q9NZT2,O96029, Q4VXW5, Q96CM2, Q9BQW1, Q9H4H0, Q9H7J5 Q9NZT3, Q9NZT4, |
| UniProt Related Accession: | Q9NZT2 |
| Molecular Weight: | 677 |
| NCBI Full Name: | Opioid growth factor receptor |
| NCBI Synonym Full Names: | opioid growth factor receptor |
| NCBI Official Symbol: | OGFR |
| NCBI Protein Information: | opioid growth factor receptor; protein 7-60; zeta-type opioid receptor |
| UniProt Protein Name: | Opioid growth factor receptor |
| UniProt Synonym Protein Names: | Protein 7-60; Zeta-type opioid receptor |
| Protein Family: | Opioid growth factor receptor |
| UniProt Gene Name: | OGFR |
| UniProt Entry Name: | OGFR_HUMAN |
 | Western blot analysis of extracts of various cell lines, using OGFR antibody (CAB7074) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded human stomach using OGFR antibody (CAB7074) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded rat kidney using OGFR antibody (CAB7074) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse stomach using OGFR antibody (CAB7074) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of MCF7 cells using OGFR antibody (CAB7074). Blue: DAPI for nuclear staining. |
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