Anti-ODF1 Antibody (CAB16023)
- SKU:
- CAB16023
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
| Antibody Name: | Anti-ODF1 Antibody |
| Antibody SKU: | CAB16023 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-180 of human ODF1 (NP_077721.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse testis, Rat testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-180 of human ODF1 (NP_077721.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LYCL RPSL RSLE RKAI RAIE DEKR ELAK LRRT TNRI LASS CCSS NILG SVNV CGFE PDQV KVRV KDGK VCVS AERE NRYD CLGS KKYS YMNI CKEF SLPP C |
| Gene ID: | 4956 |
| Uniprot: | Q14990 |
| Cellular Location: | |
| Calculated MW: | 28kDa |
| Observed MW: | 28kDa |
| Synonyms: | ODF1, CT133, HSPB10, ODF, ODF2, ODF27, ODFP, ODFPG, ODFPGA, ODFPGB, RT7, SODF |
| Background: | The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. The human outer dense fibers contains at least 10 major proteins and this gene encodes the main protein. |
| UniProt Protein Function: | ODFP1: Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. |
| UniProt Protein Details: | Protein type:Cancer Testis Antigen (CTA) Chromosomal Location of Human Ortholog: 8q22.3 Cellular Component: outer dense fiber; nucleus Molecular Function:protein domain specific binding Biological Process: multicellular organismal development; spermatogenesis; cell differentiation |
| NCBI Summary: | The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. The human outer dense fibers contains at least 10 major proteins and this gene encodes the main protein. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q14990 |
| NCBI GenInfo Identifier: | 194248060 |
| NCBI Gene ID: | 4956 |
| NCBI Accession: | NP_077721.2 |
| UniProt Secondary Accession: | Q14990,Q3SX72, |
| UniProt Related Accession: | Q14990 |
| Molecular Weight: | 28,366 Da |
| NCBI Full Name: | outer dense fiber protein 1 |
| NCBI Synonym Full Names: | outer dense fiber of sperm tails 1 |
| NCBI Official Symbol: | ODF1 |
| NCBI Official Synonym Symbols: | ODF; RT7; ODF2; ODFP; SODF; CT133; ODF27; ODFPG; HSPB10; ODFPGA; ODFPGB |
| NCBI Protein Information: | outer dense fiber protein 1; cancer/testis antigen 133; outer dense fiber of sperm tails, 27-kD |
| UniProt Protein Name: | Outer dense fiber protein 1 |
| UniProt Gene Name: | ODF1 |
| UniProt Entry Name: | ODFP1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ODF1 antibody (CAB16023) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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