Anti-NRAP Antibody (CAB12813)
- SKU:
- CAB12813
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-NRAP Antibody |
| Antibody SKU: | CAB12813 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human NRAP (NP_001248392.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:1000 |
| Reactivity: | Human |
| Positive Samples: | SH-SY5Y |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human NRAP (NP_001248392.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MNVQ PCSR CGYG VYPA EKIS CIDQ IWHK ACFH CEVC KMML SVNN FVSH QKKP YCHA HNPK NNTF TSVY HTPL NLNV RTFP EAIS GIHD QEDG EQCK SVFH WDMK SKDK EGAP NRQP LANE RAYW TGYG EGNA WCPG ALPD PEIV RMVE ARKS LGEE YTED YEQP RGKG SFPA MITP AYQR AKKA NQLA SQVE YKRG HDER ISRF STVV DTPE LLRS KAGA QLQS DVRY TEDY EQQR GKGS FPAM ITPA YQIA KRAN ELAS DVRY HQQY QKEM RGMA GPAI GAEG ILTR ECAD QYGQ GYPE |
| Gene ID: | 4892 |
| Uniprot: | Q86VF7 |
| Cellular Location: | |
| Calculated MW: | 192kDa/193kDa/197kDa |
| Observed MW: | 197kDa |
| Synonyms: | NRAP, N-RAP |
| Background: |
| UniProt Protein Function: | NRAP: May be involved in anchoring the terminal actin filaments in the myofibril to the membrane and in transmitting tension from the myofibrils to the extracellular matrix. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 10q25.3 Cellular Component: fascia adherens; muscle tendon junction Molecular Function:actin binding; muscle alpha-actinin binding; protein binding |
| UniProt Code: | Q86VF7 |
| NCBI GenInfo Identifier: | 115502505 |
| NCBI Gene ID: | 4892 |
| NCBI Accession: | Q86VF7.2 |
| UniProt Secondary Accession: | Q86VF7,O15500, Q5VWI3, Q5VWI4, Q6MZK3, Q6N026, Q6N059 Q6NSH8, Q6PDB0, Q719H6, Q86TC5, Q86TD6, |
| UniProt Related Accession: | Q86VF7 |
| Molecular Weight: | 197kDa |
| NCBI Full Name: | Nebulin-related-anchoring protein |
| NCBI Synonym Full Names: | nebulin related anchoring protein |
| NCBI Official Symbol: | NRAP |
| NCBI Official Synonym Symbols: | N-RAP |
| NCBI Protein Information: | nebulin-related-anchoring protein |
| UniProt Protein Name: | Nebulin-related-anchoring protein |
| Protein Family: | Nebulin-related-anchoring protein |
| UniProt Gene Name: | NRAP |
 | Western blot analysis of extracts of SH-SY5Y cells, using NRAP antibody (CAB12813) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s. |
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