Anti-NQO2 Antibody (CAB3846)
- SKU:
- CAB3846
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-NQO2 Antibody |
| Antibody SKU: | CAB3846 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human NQO2 |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse liver, Mouse kidney, Mouse thymus, Rat kidney |
| Immunogen: | A synthesized peptide derived from human NQO2 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 4835 |
| Uniprot: | P16083 |
| Cellular Location: | |
| Calculated MW: | 26kDa |
| Observed MW: | 26KDa |
| Synonyms: | DHQV, DIA6, NMOR2, QR2 |
| Background: | This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] |
| UniProt Protein Function: | NQO2: The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. Belongs to the NAD(P)H dehydrogenase (quinone) family. |
| UniProt Protein Details: | Protein type:Oxidoreductase; EC 1.10.99.2 Chromosomal Location of Human Ortholog: 6p25.2 Cellular Component: nucleoplasm; cytoplasm Molecular Function:electron carrier activity; dihydronicotinamide riboside quinone reductase activity; NADPH dehydrogenase (quinone) activity; metal ion binding Biological Process: memory Disease: Breast Cancer |
| NCBI Summary: | This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] |
| UniProt Code: | P16083 |
| NCBI GenInfo Identifier: | 317373581 |
| NCBI Gene ID: | 4835 |
| NCBI Accession: | P16083.5 |
| UniProt Secondary Accession: | P16083,Q9JI75, |
| UniProt Related Accession: | P16083 |
| Molecular Weight: | 231 |
| NCBI Full Name: | Ribosyldihydronicotinamide dehydrogenase |
| NCBI Synonym Full Names: | NAD(P)H dehydrogenase, quinone 2 |
| NCBI Official Symbol: | NQO2 |
| NCBI Official Synonym Symbols: | QR2; DHQV; DIA6; NMOR2 |
| NCBI Protein Information: | ribosyldihydronicotinamide dehydrogenase [quinone]; ribosyldihydronicotinamide dehydrogenase [quinone]; quinone reductase 2; NRH:quinone oxidoreductase 2; NAD(P)H menadione oxidoreductase-1, dioxin-inducible-2 |
| UniProt Protein Name: | Ribosyldihydronicotinamide dehydrogenase [quinone] |
| UniProt Synonym Protein Names: | NRH dehydrogenase [quinone] 2; NRH:quinone oxidoreductase 2; Quinone reductase 2; QR2 |
| Protein Family: | NADH-quinone oxidoreductase |
| UniProt Gene Name: | NQO2 |
| UniProt Entry Name: | NQO2_HUMAN |
 | Western blot - NQO2 Rabbit mAb (CAB3846) |
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