Anti-NOP14 Antibody (CAB10361)
- SKU:
- CAB10361
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-NOP14 Antibody |
| Antibody SKU: | CAB10361 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human NOP14 (NP_001278908.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | HeLa, U-87MG, HT-29, Jurkat, MCF7 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human NOP14 (NP_001278908.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MAKA KKVG ARRK ASGA PAGA RGGP AKAN SNPF EVKV NRQK FQIL GRKT RHDV GLPG VSRA RALR KRTQ TLLK EYKE RDKS NVFR DKRF GEYN SNMS PEEK MMKR FALE QQRH HEKK SIYN LNED EELT HYGQ SLAD IEKH NDIV DSDS DAED RGTL SAEL TAAH FGGG GGLL HKKT QQEG EERE KPKS RKEL IEEL IAKS KQEK RERQ AQRE DALE LTEK LDQD WKEI QTLL SHKT PKSE |
| Gene ID: | 8602 |
| Uniprot: | P78316 |
| Cellular Location: | Nucleus, nucleolus |
| Calculated MW: | 91kDa/97kDa |
| Observed MW: | 115kDa |
| Synonyms: | NOP14, C4orf9, NOL14, RES4-25, RES425, UTP2 |
| Background: | This gene encodes a protein that plays a role in pre-18s rRNA processing and small ribosomal subunit assembly. The encoded protein may be involved in the regulation of pancreatic cancer cell proliferation and migration. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | NOP14: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm. Belongs to the NOP14 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Nucleolus Chromosomal Location of Human Ortholog: 4p16.3 Cellular Component: membrane; mitochondrion; nucleolus; nucleoplasm; nucleus; small subunit processome Molecular Function:enzyme binding; RNA binding; snoRNA binding Biological Process: endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); maturation of SSU-rRNA; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ribosomal small subunit biogenesis and assembly; rRNA processing |
| NCBI Summary: | This gene encodes a protein that plays a role in pre-18s rRNA processing and small ribosomal subunit assembly. The encoded protein may be involved in the regulation of pancreatic cancer cell proliferation and migration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] |
| UniProt Code: | P78316 |
| NCBI GenInfo Identifier: | 56404449 |
| NCBI Gene ID: | 8602 |
| NCBI Accession: | P78316.3 |
| UniProt Secondary Accession: | P78316,Q7LGI5, Q7Z6K0, Q8TBR6, D3DVR6, |
| UniProt Related Accession: | P78316 |
| Molecular Weight: | 98kDa |
| NCBI Full Name: | Nucleolar protein 14 |
| NCBI Synonym Full Names: | NOP14 nucleolar protein |
| NCBI Official Symbol: | NOP14 |
| NCBI Official Synonym Symbols: | UTP2; NOL14; C4orf9; RES425; RES4-25 |
| NCBI Protein Information: | nucleolar protein 14 |
| UniProt Protein Name: | Nucleolar protein 14 |
| UniProt Synonym Protein Names: | Nucleolar complex protein 14 |
| Protein Family: | Nucleolar protein |
| UniProt Gene Name: | NOP14 |
 | Western blot analysis of extracts of various cell lines, using NOP14 antibody (CAB10361) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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