Anti-NOL3 Antibody (CAB6319)
- SKU:
- CAB6319
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
| Antibody Name: | Anti-NOL3 Antibody |
| Antibody SKU: | CAB6319 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-208 of human NOL3 (NP_003937.1). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:10 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | BT-474, MCF7, SW620, U-937, SW480, Mouse heart, Mouse lung, Mouse skeletal muscle, Rat heart |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-208 of human NOL3 (NP_003937.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MGNA QERP SETI DRER KRLV ETLQ ADSG LLLD ALLA RGVL TGPE YEAL DALP DAER RVRR LLLL VQGK GEAA CQEL LRCA QRTA GAPD PAWD WQHV GPGY RDRS YDPP CPGH WTPE APGS GTTC PGLP RASD PDEA GGPE GSEA VQSG TPEE PEPE LEAE ASKE AEPE PEPE PELE PEAE AEPE PELE PEPD PEPE PDFE ERDE SEDS |
| Gene ID: | 8996 |
| Uniprot: | O60936 |
| Cellular Location: | Cytoplasm, Lipid-anchor, Membrane, Mitochondrion, Nucleus, Sarcoplasmic reticulum, nucleolus |
| Calculated MW: | 22kDa/24kDa/29kDa |
| Observed MW: | 26kDa |
| Synonyms: | NOL3, ARC, FCM, MYP, NOP, NOP30 |
| Background: | This gene encodes an anti-apoptotic protein that has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53. Multiple transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | Isoform 1: May be involved in RNA splicing. |
| NCBI Summary: | This gene encodes an anti-apoptotic protein that has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010] |
| UniProt Code: | O60936 |
| NCBI GenInfo Identifier: | 20455079 |
| NCBI Gene ID: | 8996 |
| NCBI Accession: | O60936.1 |
| UniProt Secondary Accession: | O60936,O60937, B4DFL0, |
| UniProt Related Accession: | O60936 |
| Molecular Weight: | 29,355 Da |
| NCBI Full Name: | Nucleolar protein 3 |
| NCBI Synonym Full Names: | nucleolar protein 3 (apoptosis repressor with CARD domain) |
| NCBI Official Symbol: | NOL3 |
| NCBI Official Synonym Symbols: | ARC; FCM; MYP; NOP; NOP30 |
| NCBI Protein Information: | nucleolar protein 3; nucleolar protein of 30 kDa; muscle-enriched cytoplasmic protein |
| UniProt Protein Name: | Nucleolar protein 3 |
| UniProt Synonym Protein Names: | Apoptosis repressor with CARD; Muscle-enriched cytoplasmic protein; Myp; Nucleolar protein of 30 kDa; Nop30 |
| Protein Family: | Nucleolar protein |
| UniProt Gene Name: | NOL3 |
| UniProt Entry Name: | NOL3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using NOL3 antibody (CAB6319) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s. |
 | Immunohistochemistry of paraffin-embedded rat testis using NOL3 antibody (CAB6319) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded human breast using NOL3 antibody (CAB6319) at dilution of 1:100 (40x lens). |
 | Immunofluorescence analysis of U2OS cells using NOL3 antibody (CAB6319). Blue: DAPI for nuclear staining. |
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