Anti-NEUROG1 Antibody (CAB3110)
- SKU:
- CAB3110
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Developmental Biology
Frequently bought together:
Description
| Antibody Name: | Anti-NEUROG1 Antibody |
| Antibody SKU: | CAB3110 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide of human NEUROG1 |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:1000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | SH-SY5Y, THP-1, U-87MG, HepG2, Mouse testis |
| Immunogen: | A synthetic peptide of human NEUROG1 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 4762 |
| Uniprot: | Q92886 |
| Cellular Location: | Nucleus |
| Calculated MW: | 25kDa |
| Observed MW: | 25kDa |
| Synonyms: | NEUROG1, AKA, Math4C, NEUROD3, bHLHa6, ngn1 |
| Background: |
| UniProt Protein Function: | neurogenin 1: Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis. |
| UniProt Protein Details: | Protein type:Transcription factor; Cell development/differentiation; DNA-binding Chromosomal Location of Human Ortholog: 5q23-q31 Cellular Component: perikaryon; nucleus Molecular Function:protein dimerization activity; DNA binding; chromatin binding; transcription factor activity Biological Process: neuron differentiation; regulation of transcription from RNA polymerase II promoter; nervous system development; inner ear morphogenesis; cell fate commitment; transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription factor activity; positive regulation of neuron differentiation; positive regulation of exit from mitosis |
| UniProt Code: | Q92886 |
| NCBI GenInfo Identifier: | 37538313 |
| NCBI Gene ID: | 4762 |
| NCBI Accession: | Q92886.2 |
| UniProt Related Accession: | Q92886 |
| Molecular Weight: | |
| NCBI Full Name: | Neurogenin-1 |
| NCBI Synonym Full Names: | neurogenin 1 |
| NCBI Official Symbol: | NEUROG1 |
| NCBI Official Synonym Symbols: | AKA; ngn1; Math4C; bHLHa6; NEUROD3 |
| NCBI Protein Information: | neurogenin-1 |
| UniProt Protein Name: | Neurogenin-1 |
| UniProt Synonym Protein Names: | Class A basic helix-loop-helix protein 6; bHLHa6; Neurogenic basic-helix-loop-helix protein; Neurogenic differentiation factor 3; NeuroD3 |
| UniProt Gene Name: | NEUROG1 |
| UniProt Entry Name: | NGN1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using NEUROG1 antibody (CAB3110) at 1:400 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. |
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