Anti-NAT8 Antibody (CAB7759)
- SKU:
- CAB7759
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-NAT8 Antibody |
| Antibody SKU: | CAB7759 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human NAT8 |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, Mouse spleen, Mouse testis, Mouse lung, Rat kidney |
| Immunogen: | Recombinant protein of human NAT8 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 9027 |
| Uniprot: | Q9UHE5 |
| Cellular Location: | Endoplasmic reticulum membrane, Endoplasmic reticulum-Golgi intermediate compartment membrane, Single-pass type II membrane protein |
| Calculated MW: | 25kDa |
| Observed MW: | 26kDa |
| Synonyms: | NAT8, ATase2, CCNAT, CML1, GLA, Hcml1, TSC501, TSC510 |
| Background: | This gene, isolated using the differential display method to detect tissue-specific genes, is specifically expressed in kidney and liver. The encoded protein shows amino acid sequence similarity to N-acetyltransferases. A similar protein in Xenopus affects cell adhesion and gastrulation movements, and may be localized in the secretory pathway. A highly similar paralog is found in a cluster with this gene. |
| UniProt Protein Function: | NAT8: Plays a role in regulation of gastrulation. Belongs to the camello family. |
| UniProt Protein Details: | Protein type:EC 2.3.1.80; Membrane protein, integral; Cell adhesion; Membrane protein, multi-pass; Acetyltransferase Chromosomal Location of Human Ortholog: 2p13.2 Cellular Component: endoplasmic reticulum membrane; ER-Golgi intermediate compartment; ER-Golgi intermediate compartment membrane; integral to membrane Molecular Function:cysteine-S-conjugate N-acetyltransferase activity; lysine N-acetyltransferase activity; protein binding Biological Process: beta-amyloid metabolic process; cellular protein metabolic process; glutathione metabolic process; negative regulation of apoptosis; peptidyl-lysine N6-acetylation; response to drug |
| NCBI Summary: | This gene, isolated using the differential display method to detect tissue-specific genes, is specifically expressed in kidney and liver. The encoded protein shows amino acid sequence similarity to N-acetyltransferases. A similar protein in Xenopus affects cell adhesion and gastrulation movements, and may be localized in the secretory pathway. A highly similar paralog is found in a cluster with this gene. [provided by RefSeq, Sep 2008] |
| UniProt Code: | Q9UHE5 |
| NCBI GenInfo Identifier: | 145566894 |
| NCBI Gene ID: | 9027 |
| NCBI Accession: | Q9UHE5.2 |
| UniProt Secondary Accession: | Q9UHE5,O75839, Q6LEU4, Q96QI8, Q9UQ17, |
| UniProt Related Accession: | Q9UHE5 |
| Molecular Weight: | 25,619 Da |
| NCBI Full Name: | N-acetyltransferase 8 |
| NCBI Synonym Full Names: | N-acetyltransferase 8 (putative) |
| NCBI Official Symbol: | NAT8 |
| NCBI Official Synonym Symbols: | GLA; CML1; CCNAT; Hcml1; ATase2; TSC501; TSC510 |
| NCBI Protein Information: | N-acetyltransferase 8 |
| UniProt Protein Name: | N-acetyltransferase 8 |
| UniProt Synonym Protein Names: | Acetyltransferase 2; ATase2; Camello-like protein 1; Cysteinyl-conjugate N-acetyltransferase (EC:2.3.1.80); CCNAT |
| UniProt Gene Name: | NAT8 |
| UniProt Entry Name: | NAT8_HUMAN |
 | Western blot analysis of extracts of various cell lines, using NAT8 antibody (CAB7759) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded mouse brain using NAT8 antibody (CAB7759) (40x lens). |
 | Immunohistochemistry of paraffin-embedded rat kidney using NAT8 antibody (CAB7759) (40x lens). |
 | Immunohistochemistry of paraffin-embedded human stomach using NAT8 antibody (CAB7759) (40x lens). |
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