Anti-MTMR8 Antibody (CAB17723)
- SKU:
- CAB17723
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| Antibody Name: | Anti-MTMR8 Antibody |
| Antibody SKU: | CAB17723 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 430-560 of human MTMR8 (NP_060147.2). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-87MG, SKOV3, HT-29 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 430-560 of human MTMR8 (NP_060147.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | HVFS CQFG NFLG NCQK DRED LRVY EKTH SVWP FLVQ RKPD FRNP LYKG FTMY GVLN PSTV PYNI QFWC GMYN RFDK GLQP KQSM LESL LEIK KQRA MLET DVHE LEKK LKVR DEPP EEIC TCSQ LGNI LSQ |
| Gene ID: | 55613 |
| Uniprot: | Q96EF0 |
| Cellular Location: | |
| Calculated MW: | 66kDa/78kDa |
| Observed MW: | 79kDa |
 | Western blot - MTMR8 Rabbit pAb (CAB17723) |
| Synonyms: | MTMR8 |
| Background: | This gene encodes a member of the myotubularin-related family and is part of the MTMR6 subgroup. Family members are dual-specificity phosphatases and the encoded protein contains a phosphoinositide-binding domain (PID) and a SET-interacting domain (SID). Defects in other family members have been found in myotubular myopathic diseases. [provided by RefSeq, Mar 2010] |
| UniProt Protein Function: | MTMR8: Phosphatase that acts on lipids with a phosphoinositol headgroup (Probable). Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Protein phosphatase, tyrosine (non-receptor); EC 3.1.3.-; Phosphatase, lipid Chromosomal Location of Human Ortholog: Xq11.2 Cellular Component: nuclear envelope Molecular Function:protein tyrosine phosphatase activity |
| NCBI Summary: | This gene encodes a member of the myotubularin-related family and is part of the MTMR6 subgroup. Family members are dual-specificity phosphatases and the encoded protein contains a phosphoinositide-binding domain (PID) and a SET-interacting domain (SID). Defects in other family members have been found in myotubular myopathic diseases. [provided by RefSeq, Mar 2010] |
| UniProt Code: | Q96EF0 |
| NCBI GenInfo Identifier: | 74751838 |
| NCBI Gene ID: | 55613 |
| NCBI Accession: | Q96EF0.1 |
| UniProt Secondary Accession: | Q96EF0,Q5JT99, Q9NXP6, |
| UniProt Related Accession: | Q96EF0 |
| Molecular Weight: | 704 |
| NCBI Full Name: | Myotubularin-related protein 8 |
| NCBI Synonym Full Names: | myotubularin related protein 8 |
| NCBI Official Symbol: | MTMR8 |
| NCBI Protein Information: | myotubularin-related protein 8 |
| UniProt Protein Name: | Myotubularin-related protein 8 |
| Protein Family: | Myotubularin-related protein |
| UniProt Gene Name: | MTMR8 |
| UniProt Entry Name: | MTMR8_HUMAN |
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