Anti-MTF2 Antibody (CAB7077)

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SKU:
CAB7077
Product type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Frequently bought together:

Description

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Antibody Name:Anti-MTF2 Antibody
Antibody SKU:CAB7077
Antibody Size:20uL, 50uL, 100uL
Application:WB IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human MTF2 (NP_001157864.1).
Application:WB IF
Recommended Dilution:WB 1:500 - 1:2000 IF 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:HL-60, HepG2, Mouse brain, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human MTF2 (NP_001157864.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MRDS TGAG NSLV HKRS PLRR NQKT PTSL TKLS LQDG HKAK KPAC KFEE GQDV LARW SDGL FYLG TIKK INIL KQSC FIIF EDSS KSWV LWKD IQTG ATGS GEMV CTIC QEEY SEAP NEMV ICDK CGQG YHQL CHTP HIDS SVID SDEK WLCR QCVF ATTT KRGG ALKK GPNA KALQ VMKQ TLPY SVAD LE
Gene ID:22823
Uniprot:Q9Y483
Cellular Location:Nucleus
Calculated MW:29kDa/55kDa/60kDa/67kDa
Observed MW:67kDa
Synonyms:MTF2, M96, PCL2, TDRD19A, dJ976O13.2
Background:
UniProt Protein Function:MTF2: Binds to the metal-regulating-element (MRE) of metallothionein-1A gene promoter. Binding is zinc-dependent. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:DNA-binding

Chromosomal Location of Human Ortholog: 1p22.1

Cellular Component: nucleoplasm; ESC/E(Z) complex; cytoplasm; nucleus

Molecular Function:DNA binding; zinc ion binding; methylated histone residue binding

Biological Process: segment specification; negative regulation of gene expression, epigenetic; stem cell maintenance; gene expression; positive regulation of transcription from RNA polymerase II promoter; stem cell differentiation; chromatin modification; negative regulation of transcription from RNA polymerase II promoter; regulation of gene expression, epigenetic

UniProt Code:Q9Y483
NCBI GenInfo Identifier:317373393
NCBI Gene ID:22823
NCBI Accession:Q9Y483.2
UniProt Secondary Accession:Q9Y483,Q9UES9, Q9UP40, A6NGQ9, A8K2Q3, B1AKT5, B1AKT6
UniProt Related Accession:Q9Y483
Molecular Weight:593
NCBI Full Name:Metal-response element-binding transcription factor 2
NCBI Synonym Full Names:metal response element binding transcription factor 2
NCBI Official Symbol:MTF2  
NCBI Official Synonym Symbols:M96; PCL2; TDRD19A; dJ976O13.2  
NCBI Protein Information:metal-response element-binding transcription factor 2; hPCl2; polycomb-like 2; polycomb-like protein 2; tudor domain containing 19A; putative DNA binding protein; metal regulatory transcription factor 2; metal-response element DNA-binding protein M96; metal response element-binding transcription factor 2
UniProt Protein Name:Metal-response element-binding transcription factor 2
UniProt Synonym Protein Names:Metal regulatory transcription factor 2; Metal-response element DNA-binding protein M96; Polycomb-like protein 2; hPCl2
Protein Family:Mitochondrial transcription factor
UniProt Gene Name:MTF2  
UniProt Entry Name:MTF2_HUMAN
Anti-MTF2 Antibody (CAB7077)Western blot analysis of extracts of various cell lines, using MTF2 antibody (CAB7077) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.
Anti-MTF2 Antibody (CAB7077)Immunofluorescence analysis of A549 cells using MTF2 antibody (CAB7077). Blue: DAPI for nuclear staining.

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