Anti-MSRB3 Antibody (CAB8005)
- SKU:
- CAB8005
- Product type:
- Antibody
- Application:
- WB
- Application:
- IF
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | MSRB3 Rabbit Polyclonal Antibody |
| Antibody SKU: | CAB8005 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-185 of human MSRB3 (NP_001026849.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse lung, Mouse testis, Mouse brain, Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-185 of human MSRB3 (NP_001026849.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MSAF NLLH LVTK SQPV ALRA CGLP SGSC RDKK NCKV VFSQ QELR KRLT PLQY HVTQ EKGT ESAF EGEY THHK DPGI YKCV VCGT PLFK SETK FDSG SGWP SFHD VINS EAIT FTDD FSYG MHRV ETSC SQCG AHLG HIFD DGPR PTGK RYCI NSAA LSFT PADS SGTA EGGS GVAS PAQA DKAE L |
| Gene ID: | 253827 |
| Uniprot: | Q8IXL7 |
| Cellular Location: | Endoplasmic reticulum, Mitochondrion |
| Calculated MW: | 20kDa |
| Observed MW: | 25kDa |
| Synonyms: | MSRB3, DFNB74 |
| Background: | The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cofactor. Several transcript variants encoding two different isoforms have been found for this gene. One of the isoforms localizes to mitochondria while the other localizes to endoplasmic reticula. |
| UniProt Protein Function: | Catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine. Isoform 2 is essential for hearing. |
| NCBI Summary: | The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cofactor. Several transcript variants encoding two different isoforms have been found for this gene. One of the isoforms localizes to mitochondria while the other localizes to endoplasmic reticula. [provided by RefSeq, Jul 2010] |
| UniProt Code: | Q8IXL7 |
| NCBI GenInfo Identifier: | 73089054 |
| NCBI Gene ID: | 253827 |
| NCBI Accession: | NP_001026849.1 |
| UniProt Secondary Accession: | Q8IXL7,Q6UXS2, B4DR19, B7ZAQ0, |
| UniProt Related Accession: | Q8IXL7 |
| Molecular Weight: | 20,010 Da |
| NCBI Full Name: | methionine-R-sulfoxide reductase B3 isoform 2 |
| NCBI Synonym Full Names: | methionine sulfoxide reductase B3 |
| NCBI Official Symbol: | MSRB3 |
| NCBI Official Synonym Symbols: | DFNB74 |
| NCBI Protein Information: | methionine-R-sulfoxide reductase B3 |
| UniProt Protein Name: | Methionine-R-sulfoxide reductase B3 |
| Protein Family: | Methionine-R-sulfoxide reductase |
| UniProt Gene Name: | MSRB3 |
| UniProt Entry Name: | MSRB3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using MSRB3 antibody (CAB8005) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
Related Products
Human anti-EPO antibody(anti-Erythropoietin antibody) ELISA Kit
