Anti-MRPL40 Antibody (CAB18191)
- SKU:
- CAB18191
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| Antibody Name: | Anti-MRPL40 Antibody |
| Antibody SKU: | CAB18191 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human MRPL40 . |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | A-549, U2OS, BxPC-3 |
| Immunogen: | Recombinant protein of human MRPL40 . |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 64976 |
| Uniprot: | Q9NQ50 |
| Cellular Location: | |
| Calculated MW: | 24kDa |
| Observed MW: | 24kDa |
 | Western blot - MRPL40 Polyclonal Antibody (CAB18191) |
| Synonyms: | URIM, L40mt, NLVCF, MRPL22, MRP-L22, MRP-L40, MRPL40 |
| Background: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome. |
| UniProt Protein Function: | MRPL40: |
| UniProt Protein Details: | Protein type:Mitochondrial Chromosomal Location of Human Ortholog: 22q11.2 Cellular Component: mitochondrial inner membrane; mitochondrial ribosome; mitochondrion; nucleolus; nucleus Molecular Function:protein binding Biological Process: anatomical structure morphogenesis; mitochondrial translation; organelle organization and biogenesis |
| NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9NQ50 |
| NCBI GenInfo Identifier: | 21263795 |
| NCBI Gene ID: | 64976 |
| NCBI Accession: | Q9NQ50.1 |
| UniProt Secondary Accession: | Q9NQ50,O95134, B3KVZ7, |
| UniProt Related Accession: | Q9NQ50 |
| Molecular Weight: | 24,490 Da |
| NCBI Full Name: | 39S ribosomal protein L40, mitochondrial |
| NCBI Synonym Full Names: | mitochondrial ribosomal protein L40 |
| NCBI Official Symbol: | MRPL40 |
| NCBI Official Synonym Symbols: | URIM; L40mt; NLVCF; MRPL22; MRP-L22; MRP-L40 |
| NCBI Protein Information: | 39S ribosomal protein L40, mitochondrial |
| UniProt Protein Name: | 39S ribosomal protein L40, mitochondrial |
| UniProt Synonym Protein Names: | Nuclear localization signal-containing protein deleted in velocardiofacial syndrome; Up-regulated in metastasis |
| Protein Family: | 39S ribosomal protein |
| UniProt Gene Name: | MRPL40 |
| UniProt Entry Name: | RM40_HUMAN |
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