Anti-MPP6 Antibody (CAB10509)
- SKU:
- CAB10509
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-MPP6 Antibody |
| Antibody SKU: | CAB10509 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 220-420 of human MPP6 (NP_057531.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:1000 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, SW480, K-562, Mouse brain, Mouse liver, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 220-420 of human MPP6 (NP_057531.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | VKCH FDYN PYND NLIP CKEA GLKF SKGE ILQI VNRE DPNW WQAS HVKE GGSA GLIP SQFL EEKR KAFV RRDW DNSG PFCG TISS KKKK KMMY LTTR NAEF DRHE IQIY EEVA KMPP FQRK TLVL IGAQ GVGR RSLK NRFI VLNP TRFG TTVP FTSR KPRE DEKD GQAY KFVS RSEM EADI KAGK YLEH GEYE GNLY GTKI D |
| Gene ID: | 51678 |
| Uniprot: | Q9NZW5 |
| Cellular Location: | Membrane, Peripheral membrane protein |
| Calculated MW: | 61kDa |
| Observed MW: | 61kDa |
| Synonyms: | MPP6, PALS2, VAM-1, VAM1, p55T |
| Background: |
| UniProt Protein Function: | VAM-1: a membrane-associated of the MAGUK family. Interacts with Lin7, which localizes to postsynaptic densities of neurons and epithelial cell-cell junctions. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Adaptor/scaffold Chromosomal Location of Human Ortholog: 7p15 Molecular Function:protein binding |
| NCBI Summary: | Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9NZW5 |
| NCBI GenInfo Identifier: | 42560556 |
| NCBI Gene ID: | 51678 |
| NCBI Accession: | Q9NZW5.2 |
| UniProt Secondary Accession: | Q9NZW5,Q9H0E1, A4D157, |
| UniProt Related Accession: | Q9NZW5 |
| Molecular Weight: | 61,117 Da |
| NCBI Full Name: | MAGUK p55 subfamily member 6 |
| NCBI Synonym Full Names: | membrane palmitoylated protein 6 |
| NCBI Official Symbol: | MPP6 |
| NCBI Official Synonym Symbols: | VAM1; p55T; PALS2; VAM-1 |
| NCBI Protein Information: | MAGUK p55 subfamily member 6 |
| UniProt Protein Name: | MAGUK p55 subfamily member 6 |
| UniProt Synonym Protein Names: | Veli-associated MAGUK 1; VAM-1 |
| Protein Family: | MAGUK p55 subfamily |
| UniProt Gene Name: | MPP6 |
| UniProt Entry Name: | MPP6_HUMAN |
 | Western blot analysis of extracts of various cell lines, using MPP6 antibody (CAB10509) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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