Anti-MPDZ Antibody (CAB15344)
- SKU:
- CAB15344
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
| Antibody Name: | Anti-MPDZ Antibody |
| Antibody SKU: | CAB15344 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1100-1380 of human MPDZ (NP_003820.2). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:200 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-251MG, LO2, 293T, Mouse brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1100-1380 of human MPDZ (NP_003820.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | SLGQ QSGR VMAL DIFS SYTG RDIP ELPE REEG EGEE SELQ NTAY SNWN QPRR VELW REPS KSLG ISIV GGRG MGSR LSNG EVMR GIFI KHVL EDSP AGKN GTLK PGDR IVEV DGMD LRDA SHEQ AVEA IRKA GNPV VFMV QSII NRPR KSPL PSLL HNLY PKYN FSST NPFA DSLQ INAD KAPS QSES EPEK APLC SVPP PPPS AFAE MGSD HTQS SASK ISQD VDKE DEFG YSWK NIRE RYGT LTGE LHMI ELEK GHSG LGLS LAGN KDRS RMSV FIVG I |
| Gene ID: | 8777 |
| Uniprot: | O75970 |
| Cellular Location: | Apical cell membrane, Cell junction, Cell membrane, Cell projection, Cytoplasmic side, Peripheral membrane protein, dendrite, postsynaptic cell membrane, postsynaptic density, synapse, synaptosome, tight junction |
| Calculated MW: | 214kDa/217kDa/218kDa/221kDa |
| Observed MW: | 321kDa |
| Synonyms: | MPDZ, HYC2, MUPP1 |
| Background: | The protein encoded by this gene has multiple PDZ domains, which are hallmarks of protein-protein interactions. The encoded protein is known to interact with the HTR2C receptor and may cause it to clump at the cell surface. Multiple transcript variants encoding different isoforms have been found for this gene. |
| NCBI Summary: | The protein encoded by this gene has multiple PDZ domains, which are hallmarks of protein-protein interactions. The encoded protein is known to interact with the HTR2C receptor and may cause it to clump at the cell surface. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015] |
| UniProt Code: | O75970 |
| NCBI GenInfo Identifier: | 148746189 |
| NCBI Gene ID: | 8777 |
| NCBI Accession: | NP_003820.2 |
| UniProt Related Accession: | O75970 |
| Molecular Weight: | 321kDa |
| NCBI Full Name: | multiple PDZ domain protein isoform 1 |
| NCBI Synonym Full Names: | multiple PDZ domain crumbs cell polarity complex component |
| NCBI Official Symbol: | MPDZ |
| NCBI Official Synonym Symbols: | HYC2; MUPP1 |
| NCBI Protein Information: | multiple PDZ domain protein |
| UniProt Protein Name: | Multiple PDZ domain protein |
| UniProt Synonym Protein Names: | Multi-PDZ domain protein 1 |
| Protein Family: | Multiple PDZ domain protein |
| UniProt Gene Name: | MPDZ |
| UniProt Entry Name: | MPDZ_HUMAN |
 | Western blot analysis of extracts of various cell lines, using MPDZ antibody (CAB15344) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 2s. |
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