Anti-Mouse IFNγ [H22] In Vivo Antibody - Low Endotoxin
- SKU:
- IVMB0033
- Product Type:
- In Vivo Monoclonal Antibody
- Clone:
- H22
- Protein:
- Interferon Gamma
- Isotype:
- Armenian Hamster IgG
- Reactivity:
- Mouse
- Synonyms:
- Immune Interferon
- Type II Interferon
- T Cell Interferon
- MAF
- IFNG
- IFG
- IFI
- Research Area:
- Interferons
- Endotoxin Level:
- Low Endotoxin
- Host Species:
- Armenian Hamster
- Applications:
- IP
- Neutralizing
- WB
Frequently bought together:
Description
system_update_altTechnical Datasheet
Product Name: | Anti-Mouse IFNγ [H22] In Vivo Antibody - Low Endotoxin |
Product Code: | IVMB0033 |
Size: | 1mg, 5mg, 25mg, 50mg, 100mg |
Clone: | H22 |
Protein: | Interferon Gamma |
Product Type: | Monoclonal Antibody |
Synonyms: | Immune Interferon, Type II Interferon, T Cell Interferon, MAF, IFNG, IFG, IFI |
Isotype: | Armenian Hamster IgG |
Reactivity: | Mouse |
Immunogen: | Purified Recombinant Mouse IFN-γ (>98%) |
Applications: | IP, N, WB |
Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
Endotoxin Level: | < 1.0 EU/mg as determined by the LAL method |
Purity: | ≥95% monomer by analytical SEC >95% by SDS Page |
Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
Storage and Handling: | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
Applications: | IP, N, WB |
Recommended Usage: | WB For Western blotting, the suggested use of clone H22 antibody is 0.6 µg/ml. |
Reactivity: | Mouse |
Host Species: | Armenian Hamster |
Specificity: | Armenian Hamster Anti-Mouse Interferon-Gamma (IFN-γ) (Clone H22) recognizes an epitope on Mouse IFN-γ. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
Immunogen: | Purified Recombinant Mouse IFN-γ (>98%) |
Concentration: | ≥ 5.0 mg/ml |
Endotoxin Level: | < 1.0 EU/mg as determined by the LAL method |
Purity: | ≥95% monomer by analytical SEC >95% by SDS Page |
Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
Storage and Handling: | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.4 It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.5 IFN-γ has antiviral, immunoregulatory, and anti-tumour properties.6
Technical Datasheet: | View |
Protein: | Interferon Gamma |
Ligand/Receptor: | IFN-&gammalRα (CDw119) dimerized with IFN-γRβ (AF-1) |
Research Area: | Immunology |
Armenian Hamster IgG Isotype Control | |
---|---|
Clone | PIP |
Isotype | Armenian Hamster IgG |
Endotoxin Level | Low Endotoxin |