Anti-MonoMethyl-Histone H3-R2 Antibody (CAB19645)
- SKU:
- CAB19645
- Product type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| Antibody Name: | Anti-MonoMethyl-Histone H3-R2 Antibody |
| Antibody SKU: | CAB19645 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IP ChIP |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Histone H3 (mono methyl R2). |
| Application: | WB IP ChIP |
| Recommended Dilution: | WB 1:500 - 1:2000 ChIP 1:20 - 1:100 |
| Reactivity: | Human, Rat |
| Positive Samples: | HeLa, C6 |
| Immunogen: | A synthesized peptide derived from human Histone H3 (mono methyl R2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 8290/8350 |
| Uniprot: | Q16695/P68431 |
| Cellular Location: | |
| Calculated MW: | 15kDa |
| Observed MW: | 17KDa |
 | Western blot - MonoMethyl-Histone H3-R2 Rabbit mAb (CAB19645) |
| Synonyms: | H3/A, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H3FA, H3C10, H3C11, H3C12, HIST1H3A |
| Background: | This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. |
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