Anti-Monoamine Oxidase B Antibody (CAB11597)
- SKU:
- CAB11597
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-Monoamine Oxidase B Antibody |
Antibody SKU: | CAB11597 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IHC |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | A synthesized peptide derived from human Monoamine Oxidase B |
Application: | WB IHC |
Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | HeLa, HepG2 |
Immunogen: | A synthesized peptide derived from human Monoamine Oxidase B |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 4129 |
Uniprot: | P27338 |
Cellular Location: | |
Calculated MW: | 59kDa |
Observed MW: | 59KDa |
Synonyms: | |
Background: | The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. [provided by RefSeq, Jul 2008] |
UniProt Protein Function: | MAOB: Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine. Belongs to the flavin monoamine oxidase family. |
UniProt Protein Details: | Protein type:Mitochondrial; Amino Acid Metabolism - arginine and proline; EC 1.4.3.4; Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - glycine, serine and threonine; Amino Acid Metabolism - histidine; Membrane protein, integral; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Oxidoreductase; Amino Acid Metabolism - phenylalanine; Amino Acid Metabolism - tryptophan Chromosomal Location of Human Ortholog: Xp11.23 Cellular Component: mitochondrial envelope; mitochondrial outer membrane; mitochondrion; mitochondrial inner membrane; integral to membrane Molecular Function:amine oxidase activity; protein homodimerization activity; electron carrier activity; FAD binding Biological Process: response to drug; negative regulation of serotonin secretion; positive regulation of dopamine metabolic process; response to selenium ion; response to ethanol; substantia nigra development; dopamine catabolic process; response to toxin; xenobiotic metabolic process; response to lipopolysaccharide; hydrogen peroxide biosynthetic process; response to corticosterone stimulus; response to aluminum ion |
NCBI Summary: | The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. [provided by RefSeq, Jul 2008] |
UniProt Code: | P27338 |
NCBI GenInfo Identifier: | 113980 |
NCBI Gene ID: | 4129 |
NCBI Accession: | P27338.3 |
UniProt Secondary Accession: | P27338,Q7Z6S2, B2R6R3, B7Z5H3, D3DWC3, |
UniProt Related Accession: | P27338 |
Molecular Weight: | 520 |
NCBI Full Name: | Amine oxidase |
NCBI Synonym Full Names: | monoamine oxidase B |
NCBI Official Symbol: | MAOB |
NCBI Protein Information: | amine oxidase [flavin-containing] B; amine oxidase [flavin-containing] B; MAO-B; MAO, brain; MAO, platelet; tyramine oxidase; adrenalin oxidase; monoamine oxidase type B |
UniProt Protein Name: | Amine oxidase [flavin-containing] B |
UniProt Synonym Protein Names: | Monoamine oxidase type B; MAO-B |
Protein Family: | Amine oxidase |
UniProt Gene Name: | MAOB |
UniProt Entry Name: | AOFB_HUMAN |