Anti-MCHR1 Antibody (CAB18111)
- SKU:
- CAB18111
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| Antibody Name: | Anti-MCHR1 Antibody |
| Antibody SKU: | CAB18111 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human MCHR1. |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse brain, Rat brain, Rat heart |
| Immunogen: | Recombinant protein of human MCHR1. |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 2847 |
| Uniprot: | Q99705 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 46kDa |
 | Western blot - MCHR1 Polyclonal Antibody (CAB18111) |
| Synonyms: | GPR24, MCH-1R, MCH1R, SLC-1, SLC1, MCHR1 |
| Background: |
| UniProt Protein Function: | MCHR1: Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 22q13.2 Cellular Component: integral to plasma membrane; nonmotile primary cilium; plasma membrane Molecular Function:G-protein coupled receptor activity; protein C-terminus binding; neuropeptide receptor activity; hormone binding; melanin-concentrating hormone receptor activity Biological Process: G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; generation of precursor metabolites and energy; neuropeptide signaling pathway; feeding behavior; G-protein signaling, adenylate cyclase inhibiting pathway; positive regulation of calcium ion transport |
| NCBI Summary: | The protein encoded by this gene, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q99705 |
| NCBI GenInfo Identifier: | 88758590 |
| NCBI Gene ID: | 2847 |
| NCBI Accession: | NP_005288.3 |
| UniProt Secondary Accession: | Q99705,Q5R3J1, Q96S47, Q9BV08, B2RBX6, |
| UniProt Related Accession: | Q99705 |
| Molecular Weight: | 45,963 Da |
| NCBI Full Name: | melanin-concentrating hormone receptor 1 |
| NCBI Synonym Full Names: | melanin-concentrating hormone receptor 1 |
| NCBI Official Symbol: | MCHR1 |
| NCBI Official Synonym Symbols: | SLC1; GPR24; MCH1R; SLC-1; MCH-1R |
| NCBI Protein Information: | melanin-concentrating hormone receptor 1; MCH receptor 1; G protein-coupled receptor 24; somatostatin receptor-like protein |
| UniProt Protein Name: | Melanin-concentrating hormone receptor 1 |
| UniProt Synonym Protein Names: | G-protein coupled receptor 24; MCH-1R; MCH1R; MCHR; SLC-1; Somatostatin receptor-like protein |
| Protein Family: | Melanin-concentrating hormone receptor |
| UniProt Gene Name: | MCHR1 |
| UniProt Entry Name: | MCHR1_HUMAN |
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Mouse Melanin-concentrating hormone receptor 1 (Mchr1) ELISA Kit
