Anti-MATN4 Antibody (CAB2761)

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SKU:
CAB2761
Product type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Frequently bought together:

Description

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Antibody Name:Anti-MATN4 Antibody
Antibody SKU:CAB2761
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 221-540 of human MATN4 (NP_085080.1).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:100 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:HepG2, NCI-H460, Mouse heart, Rat kidney
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 221-540 of human MATN4 (NP_085080.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:FGNH SCQH ECVS TPGG PRCH CREG HDLQ PDGR SCQV RDLC NGVD HGCE FQCV SEGL SYRC LCPE GRQL QADG KSCN RCRE GHVD LVLL VDGS KSVR PQNF ELVK RFVN QIVD FLDV SPEG TRVG LVQF SSRV RTEF PLGR YGTA AEVK QAVL AVEY MERG TMTG LALR HMVE HSFS EAQG ARPR ALNV PRVG LVFT DGRS QDDI SVWA ARAK EEGI VMYA VGVG KAVE AELR EIAS EPAE LHVS YAPD FGTM THLL ENLR GSIC PEEG ISAG TELR SPCE CESL VEFQ GRTL GALE SLTL NLAQ LTAR LEDL ENQL ANQK
Gene ID:8785
Uniprot:O95460
Cellular Location:Secreted
Calculated MW:47kDa/59kDa/64kDa/68kDa
Observed MW:73kDa
Synonyms:MATN4
Background:This gene encodes a member of von Willebrand factor A domain-containing protein family. The proteins of this family are thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This family member is thought to be play a role in reorganizing and regenerating the corneal matrix in granular and lattice type I dystrophies. It may also be involved in wound healing in the dentin-pulp complex. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:MATN4: Major component of the extracellular matrix of cartilage. 4 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 20q13.12

Cellular Component: extracellular region

Molecular Function:protein binding

Biological Process: extracellular matrix organization and biogenesis; response to axon injury

NCBI Summary:This gene encodes a member of von Willebrand factor A domain-containing protein family. The proteins of this family are thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This family member is thought to be play a role in reorganizing and regenerating the corneal matrix in granular and lattice type I dystrophies. It may also be involved in wound healing in the dentin-pulp complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
UniProt Code:O95460
NCBI GenInfo Identifier:73920229
NCBI Gene ID:8785
NCBI Accession:O95460.3
UniProt Related Accession:O95460
Molecular Weight:73kDa
NCBI Full Name:Matrilin-4
NCBI Synonym Full Names:matrilin 4
NCBI Official Symbol:MATN4  
NCBI Protein Information:matrilin-4
UniProt Protein Name:Matrilin-4
Protein Family:Matrilin
UniProt Gene Name:MATN4  
UniProt Entry Name:MATN4_HUMAN
Anti-MATN4 Antibody (CAB2761)Western blot analysis of extracts of various cell lines, using MATN4 antibody (CAB2761) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.

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