Anti-MAPRE3 Antibody (CAB9591)
- SKU:
- CAB9591
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| Antibody Name: | Anti-MAPRE3 Antibody |
| Antibody SKU: | CAB9591 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-281 of human MAPRE3 (NP_036458.2). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:1000 - 1:3000 IHC 1:50 - 1:200 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse brain, Mouse kidney |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-281 of human MAPRE3 (NP_036458.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MAVN VYST SVTS ENLS RHDM LAWV NDSL HLNY TKIE QLCS GAAY CQFM DMLF PGCV HLRK VKFQ AKLE HEYI HNFK VLQA AFKK MGVD KIIP VEKL VKGK FQDN FEFI QWFK KFFD ANYD GKDY NPLL ARQG QDVA PPPN PGDQ IFNK SKKL IGTA VPQR TSPT GPKN MQTS GRLS NVAP PCIL RKNP PSAR NGGH ETDA QILE LNQQ LVDL KLTV DGLE KERD FYFS KLRD IELI CQEH ESEN SPVI SGII GILY ATEE GFAP PEDD EIEE HQQE DQDE Y |
| Gene ID: | 22924 |
| Uniprot: | Q9UPY8 |
| Cellular Location: | Cytoplasm, cytoskeleton |
| Calculated MW: | 30kDa/31kDa |
| Observed MW: | 35kDa |
| Synonyms: | MAPRE3, EB3, EBF3, EBF3-S, RP3 |
| Background: | The protein encoded by this gene is a member of the RP/EB family of genes. The protein localizes to the cytoplasmic microtubule network and binds APCL, a homolog of the adenomatous polyposis coli tumor suppressor gene. |
| UniProt Protein Function: | EB3: Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration. Belongs to the MAPRE family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Microtubule-binding Chromosomal Location of Human Ortholog: 2p23.3-p23.1 Cellular Component: microtubule cytoskeleton; cytoplasmic microtubule; perinuclear region of cytoplasm; cytoplasm; midbody Molecular Function:protein binding; microtubule binding Biological Process: mitosis; positive regulation of cyclin-dependent protein kinase activity; cell division; positive regulation of transcription, DNA-dependent |
| UniProt Code: | Q9UPY8 |
| NCBI GenInfo Identifier: | 10800412 |
| NCBI Gene ID: | |
| NCBI Accession: | NP_036458.2 |
| Molecular Weight: | ~ 32kDa |
| NCBI Full Name: | microtubule-associated protein RP/EB family member 3 |
| UniProt Protein Name: | Microtubule-associated protein RP/EB family member 3 |
| UniProt Synonym Protein Names: | EB1 protein family member 3; EBF3; End-binding protein 3; EB3; RP3 |
| UniProt Gene Name: | MAPRE3 |
| UniProt Entry Name: | MARE3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using MAPRE3 antibody (CAB9591) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded mouse bronchus using MAPRE3 antibody (CAB9591) at dilution of 1:100 (40x lens). |
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