Anti-MAN1C1 Antibody (CAB12837)
- SKU:
- CAB12837
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-MAN1C1 Antibody |
| Antibody SKU: | CAB12837 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 44-240 of human MAN1C1 (NP_065112.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | A-549, U-87MG, HepG2, Mouse liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 44-240 of human MAN1C1 (NP_065112.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | PHSS RLKR LFLA PRTQ QPGL EVVA EIAG HAPA REQE PPPN PAPA APAP GEDD PSSW ASPR RRKG GLRR TRPT GPRE EATA ARGN SIPA SRPG DEGV PFRF DFNA FRSR LRHP VLGT RADE SQEP QSQV RAQR EKIK EMMQ FAWQ SYKR YAMG KNEL RPLT KDGY EGNM FGGL SGAT VIDS LDTL YLME LKEE FQEA K |
| Gene ID: | 57134 |
| Uniprot: | Q9NR34 |
| Cellular Location: | Golgi apparatus membrane, Single-pass type II membrane protein |
| Calculated MW: | 70kDa |
| Observed MW: | 68kDa |
| Synonyms: | MAN1C1, HMIC, MAN1A3, MAN1C, pp6318 |
| Background: |
| UniProt Protein Function: | MAN1C1: Involved in the maturation of Asn-linked oligosaccharides. Trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce first Man(8)GlcNAc(2) then Man(6)GlcNAc and a small amount of Man(5)GlcNAc. Belongs to the glycosyl hydrolase 47 family. |
| UniProt Protein Details: | Protein type:Calcium-binding; EC 3.2.1.113; Glycan Metabolism - N-glycan biosynthesis; Hydrolase; Membrane protein, integral Chromosomal Location of Human Ortholog: 1p36.11 Cellular Component: endoplasmic reticulum; Golgi membrane; integral to Golgi membrane Molecular Function:calcium ion binding; mannosyl-oligosaccharide 1,2-alpha-mannosidase activity Biological Process: N-glycan processing; protein amino acid N-linked glycosylation |
| UniProt Code: | Q9NR34 |
| NCBI GenInfo Identifier: | 17369308 |
| NCBI Gene ID: | 57134 |
| NCBI Accession: | Q9NR34.1 |
| UniProt Secondary Accession: | Q9NR34,Q9Y545, A6NNE2, B2RNP2, |
| UniProt Related Accession: | Q9NR34 |
| Molecular Weight: | 71kDa |
| NCBI Full Name: | Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC |
| NCBI Synonym Full Names: | mannosidase alpha class 1C member 1 |
| NCBI Official Symbol: | MAN1C1 |
| NCBI Official Synonym Symbols: | HMIC; MAN1C; MAN1A3; pp6318 |
| NCBI Protein Information: | mannosyl-oligosaccharide 1,2-alpha-mannosidase IC |
| UniProt Protein Name: | Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC |
| UniProt Synonym Protein Names: | HMIC; Mannosidase alpha class 1C member 1; Processing alpha-1,2-mannosidase IC; Alpha-1,2-mannosidase IC |
| Protein Family: | Mannosyl-oligosaccharide 1,2-alpha-mannosidase |
| UniProt Gene Name: | MAN1C1 |
 | Western blot analysis of extracts of various cell lines, using MAN1C1 antibody (CAB12837) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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