Anti-MAK Antibody (CAB17508)
- SKU:
- CAB17508
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| Antibody Name: | Anti-MAK Antibody |
| Antibody SKU: | CAB17508 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 370-435 of human MAK (NP_005897.1). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | Mouse lung, Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 370-435 of human MAK (NP_005897.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | TLFP SIVK NMPT KPNG TLSH KSGR RRWG QTIF KSGD SWEE LEDY DFGA SHSK KPSM GVFK EKRK KD |
| Gene ID: | 4117 |
| Uniprot: | P20794 |
| Cellular Location: | |
| Calculated MW: | |
| Observed MW: | 71kDa |
 | Western blot - MAK Polyclonal Antibody (CAB17508) |
| Synonyms: | RP62, MAK |
| Background: | The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. Mutations in this gene have been associated with ciliary defects resulting in retinitis pigmentosa 62. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] |
| UniProt Protein Function: | MAK: a protein kinase of the RCK family of kinases. It is expressed at high levels in the testis (primarily in germ cells), and in developing sensory epithelia. Localizes to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. |
| UniProt Protein Details: | Protein type:Protein kinase, CMGC; EC 2.7.11.22; Nuclear receptor co-regulator; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); CMGC group; RCK family Chromosomal Location of Human Ortholog: 6p24 Cellular Component: centrosome; midbody; nucleus; photoreceptor inner segment; photoreceptor outer segment Molecular Function:protein binding; transcription coactivator activity Biological Process: photoreceptor cell maintenance; protein amino acid autophosphorylation; protein amino acid phosphorylation Disease: Retinitis Pigmentosa 62 |
| NCBI Summary: | The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. Mutations in this gene have been associated with ciliary defects resulting in retinitis pigmentosa 62. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] |
| UniProt Code: | P20794 |
| NCBI GenInfo Identifier: | 13432166 |
| NCBI Gene ID: | 4117 |
| NCBI Accession: | P20794.2 |
| UniProt Secondary Accession: | P20794,Q547D0, Q9NUH7, F1T0K6, G1FL29, |
| UniProt Related Accession: | P20794 |
| Molecular Weight: | 66,345 Da |
| NCBI Full Name: | Serine/threonine-protein kinase MAK |
| NCBI Synonym Full Names: | male germ cell associated kinase |
| NCBI Official Symbol: | MAK |
| NCBI Official Synonym Symbols: | RP62 |
| NCBI Protein Information: | serine/threonine-protein kinase MAK |
| UniProt Protein Name: | Serine/threonine-protein kinase MAK |
| UniProt Synonym Protein Names: | Male germ cell-associated kinase |
| Protein Family: | Makatoxin |
| UniProt Gene Name: | MAK |
| UniProt Entry Name: | MAK_HUMAN |
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