Anti-LYPLA2 Antibody (CAB15792)
- SKU:
- CAB15792
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
| Antibody Name: | Anti-LYPLA2 Antibody |
| Antibody SKU: | CAB15792 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 147-231 of human LYPLA2 (NP_009191.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, HT-29, Raji, Mouse thymus, Mouse brain, Rat lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 147-231 of human LYPLA2 (NP_009191.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | CWLP LHRA FPQA ANGS AKDL AILQ CHGE LDPM VPVR FGAL TAEK LRSV VTPA RVQF KTYP GVMH SSCP QEMA AVKE FLEK LLPP V |
| Gene ID: | 11313 |
| Uniprot: | O95372 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 24kDa |
| Observed MW: | 25kDa |
| Synonyms: | LYPLA2, APT-2, APT2, DJ886K2.4 |
| Background: | Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. There are alternatively spliced transcript variants described for this gene but the full length nature is not known yet. |
| UniProt Protein Function: | LYPLA2: May hydrolyze fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has lysophospholipase activity. Deacylates GAP43. Belongs to the AB hydrolase 2 family. |
| UniProt Protein Details: | Protein type:Lipid Metabolism - glycerophospholipid; EC 3.1.2.-; Phospholipase Chromosomal Location of Human Ortholog: 1p36.11 Cellular Component: cytoplasm Molecular Function:palmitoyl-(protein) hydrolase activity Biological Process: protein depalmitoylation |
| NCBI Summary: | Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. There are alternatively spliced transcript variants described for this gene but the full length nature is not known yet. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O95372 |
| NCBI GenInfo Identifier: | 41017276 |
| NCBI Gene ID: | 11313 |
| NCBI Accession: | O95372.1 |
| UniProt Secondary Accession: | O95372,Q7Z4Z2, |
| UniProt Related Accession: | O95372 |
| Molecular Weight: | 24,737 Da |
| NCBI Full Name: | Acyl-protein thioesterase 2 |
| NCBI Synonym Full Names: | lysophospholipase II |
| NCBI Official Symbol: | LYPLA2 |
| NCBI Official Synonym Symbols: | APT2; APT-2; DJ886K2.4 |
| NCBI Protein Information: | acyl-protein thioesterase 2 |
| UniProt Protein Name: | Acyl-protein thioesterase 2 |
| UniProt Synonym Protein Names: | Lysophospholipase II; LPL-II; LysoPLA II |
| Protein Family: | Acyl-protein thioesterase |
| UniProt Gene Name: | LYPLA2 |
| UniProt Entry Name: | LYPA2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using LYPLA2 antibody (CAB15792) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 90s. |
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