Anti-LY75 Antibody (CAB10065)
- SKU:
- CAB10065
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-LY75 Antibody |
| Antibody SKU: | CAB10065 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 440-680 of human LY75 (NP_002340.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:1000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse lung |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 440-680 of human LY75 (NP_002340.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | TEVT LTYW DENE PNVP YNKT PNCV SYLG ELGQ WKVQ SCEE KLKY VCKR KGEK LNDA SSDK MCPP DEGW KRHG ETCY KIYE DEVP FGTN CNLT ITSR FEQE YLND LMKK YDKS LRKY FWTG LRDV DSCG EYNW ATVG GRRR AVTF SNWN FLEP ASPG GCVA MSTG KSVG KWEV KDCR SFKA LSIC KKMS GPLG PEEA SPKP DDPC PEGW QSFP ASLS CYKV FHAE RIVR KRNW EEAE RFCQ A |
| Gene ID: | 4065 |
| Uniprot: | O60449 |
| Cellular Location: | Membrane, Single-pass type I membrane protein |
| Calculated MW: | 19kDa/26kDa/198kDa/209kDa/215kDa |
| Observed MW: | 205kDa |
| Synonyms: | LY75, CD205, CLEC13B, DEC-205, GP200-MR6, LY-75 |
| Background: |
| UniProt Protein Function: | LY75: Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen- processing compartment. Causes reduced proliferation of B-lymphocytes. 5 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 2q24 Cellular Component: integral to plasma membrane Molecular Function:receptor activity Biological Process: immune response; inflammatory response |
| UniProt Code: | O60449 |
| NCBI GenInfo Identifier: | 317373426 |
| NCBI Gene ID: | 4065 |
| NCBI Accession: | O60449.3 |
| UniProt Secondary Accession: | O60449,O75913, Q53R46, Q53TF5, Q7Z575, Q7Z577, |
| UniProt Related Accession: | O60449 |
| Molecular Weight: | 26,183 Da |
| NCBI Full Name: | Lymphocyte antigen 75 |
| NCBI Synonym Full Names: | lymphocyte antigen 75 |
| NCBI Official Symbol: | LY75 |
| NCBI Official Synonym Symbols: | CD205; LY-75; CLEC13B; DEC-205; GP200-MR6 |
| NCBI Protein Information: | lymphocyte antigen 75 |
| UniProt Protein Name: | Lymphocyte antigen 75 |
| UniProt Synonym Protein Names: | C-type lectin domain family 13 member B; DEC-205; gp200-MR6; CD_antigen: CD205 |
| Protein Family: | Lymphocyte antigen |
| UniProt Gene Name: | LY75 |
| UniProt Entry Name: | LY75_HUMAN |
 | Western blot analysis of extracts of mouse lung, using LY75 antibody (CAB10065) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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