Anti-LTB4R2 Antibody (CAB15479)
- SKU:
- CAB15479
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-LTB4R2 Antibody |
| Antibody SKU: | CAB15479 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 254-358 of human LTB4R2 (NP_062813.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:200 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-251MG, Mouse brain, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 254-358 of human LTB4R2 (NP_062813.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | PPEG ALAK LGGA GQAA RAGT TALA FFSS SVNP VLYV FTAG DLLP RAGP RFLT RLFE GSGE ARGG GRSR EGTM ELRT TPQL KVVG QGRG NGDP GGGM EKDG PEWD L |
| Gene ID: | 56413 |
| Uniprot: | Q9NPC1 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 37kDa/41kDa |
| Observed MW: | 43kDa |
| Synonyms: | LTB4R2, BLT2, BLTR2, JULF2, KPG_004, LTB4-R 2, LTB4-R2, NOP9 |
| Background: |
| UniProt Protein Function: | LTB4R2: Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 14q12 Cellular Component: integral to plasma membrane; membrane; plasma membrane Molecular Function:leukotriene B4 receptor activity; leukotriene receptor activity; peptide receptor activity, G-protein coupled Biological Process: chemotaxis; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); inflammatory response; negative regulation of adenylate cyclase activity; neuropeptide signaling pathway |
| UniProt Code: | Q9NPC1 |
| NCBI GenInfo Identifier: | 23821812 |
| NCBI Gene ID: | 56413 |
| NCBI Accession: | Q9NPC1.1 |
| UniProt Secondary Accession: | Q9NPC1,Q5KU28, Q9NPE5, |
| UniProt Related Accession: | Q9NPC1 |
| Molecular Weight: | 37,942 Da |
| NCBI Full Name: | Leukotriene B4 receptor 2 |
| NCBI Synonym Full Names: | leukotriene B4 receptor 2 |
| NCBI Official Symbol: | LTB4R2 |
| NCBI Official Synonym Symbols: | BLT2; NOP9; BLTR2; JULF2; KPG_004; LTB4-R2; LTB4-R 2 |
| NCBI Protein Information: | leukotriene B4 receptor 2 |
| UniProt Protein Name: | Leukotriene B4 receptor 2 |
| UniProt Synonym Protein Names: | LTB4 receptor JULF2; Leukotriene B4 receptor BLT2; Seven transmembrane receptor BLTR2 |
| Protein Family: | Leukotriene B4 receptor |
| UniProt Gene Name: | LTB4R2 |
| UniProt Entry Name: | LT4R2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using LTB4R2 antibody (CAB15479). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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