Anti-LSM2 항체 (CAB7988)

Antibody Name:	LSM2 Rabbit Polyclonal Antibody
Antibody SKU:	CAB7988
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IHC IF
Reactivity:	Human
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human LSM2 (NP_067000.1).

Application:	WB IHC IF
Recommended Dilution:	WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:	Human
Positive Samples:	SW620, SKOV3

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human LSM2 (NP_067000.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	MLFY SFFK SLVG KDVV VELK NDLS ICGT LHSV DQYL NIKL TDIS VTDP EKYP HMLS VKNC FIRG SVVR YVQL PADE VDTQ LLQD AARK EALQ QKQ
Gene ID:	57819
Uniprot:	Q9Y333
Cellular Location:	Nucleus
Calculated MW:	10kDa
Observed MW:	13kDa

Synonyms:	LSM2, C6orf28, G7B, YBL026W, snRNP
Background:	This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 19.

UniProt Protein Function:	LSM2: Binds specifically to the 3'-terminal U-tract of U6 snRNA. May be involved in pre-mRNA splicing. Identified in the spliceosome C complex. LSm subunits form a heteromer with a doughnut shape. Belongs to the snRNP Sm proteins family.
UniProt Protein Details:	Protein type:RNA splicing; Spliceosome; RNA-binding Chromosomal Location of Human Ortholog: 6p21.3 Cellular Component: cytosol; nucleoplasm; U4/U6 x U5 tri-snRNP complex Molecular Function:protein binding; Ral GTPase binding; RNA binding Biological Process: nuclear mRNA splicing, via spliceosome
NCBI Summary:	This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 19. [provided by RefSeq, Nov 2011]
UniProt Code:	Q9Y333
NCBI GenInfo Identifier:	10720079
NCBI Gene ID:	57819
NCBI Accession:	Q9Y333.1
UniProt Secondary Accession:	Q9Y333,Q6FGG1,
UniProt Related Accession:	Q9Y333
Molecular Weight:	10,835 Da
NCBI Full Name:	U6 snRNA-associated Sm-like protein LSm2
NCBI Synonym Full Names:	LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
NCBI Official Symbol:	LSM2
NCBI Official Synonym Symbols:	G7B; snRNP; C6orf28; YBL026W
NCBI Protein Information:	U6 snRNA-associated Sm-like protein LSm2
UniProt Protein Name:	U6 snRNA-associated Sm-like protein LSm2
UniProt Synonym Protein Names:	Protein G7b; Small nuclear ribonuclear protein D homolog; snRNP core Sm-like protein Sm-x5
Protein Family:	Sm-like protein
UniProt Gene Name:	LSM2
UniProt Entry Name:	LSM2_HUMAN

	Western blot analysis of extracts of various cell lines, using LSM2 antibody (CAB7988) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s.
	Immunohistochemistry of paraffin-embedded human gastric cancer using LSM2 antibody (CAB7988) at dilution of 1:100 (40x lens).
	Immunofluorescence analysis of U2OS cells using LSM2 antibody (CAB7988) at dilution of 1:100. Blue: DAPI for nuclear staining.

Antibodies

LSM2 Antibody (PACO10301)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)