Anti-LIPG Antibody (CAB1891)
- SKU:
- CAB1891
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
| Antibody Name: | Anti-LIPG Antibody |
| Antibody SKU: | CAB1891 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 251-500 of human LIPG (NP_006024.1). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HepG2, A-549, Mouse liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 251-500 of human LIPG (NP_006024.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | GCGL NDVL GSIA YGTI TEVV KCEH ERAV HLFV DSLV NQDK PSFA FQCT DSNR FKKG ICLS CRKN RCNS IGYN AKKM RNKR NSKM YLKT RAGM PFRV YHYQ MKIH VFSY KNMG EIEP TFYV TLYG TNAD SQTL PLEI VERI EQNA TNTF LVYT EEDL GDLL KIQL TWEG ASQS WYNL WKEF RSYL SQPR NPGR ELNI RRIR VKSG ETQR KLTF CTED PENT SISP GREL WFRK CRDG WRMK NETS PTVE LP |
| Gene ID: | 9388 |
| Uniprot: | Q9Y5X9 |
| Cellular Location: | Secreted |
| Calculated MW: | 39kDa/56kDa |
| Observed MW: | 60kDa |
| Synonyms: | LIPG, EDL, EL, PRO719 |
| Background: | The protein encoded by this gene has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. This protein is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family. |
| UniProt Protein Function: | LIPG: Has phospholipase and triglyceride lipase activities. Hydrolyzes high density lipoproteins (HDL) more efficiently than other lipoproteins. Binds heparin. Belongs to the AB hydrolase superfamily. Lipase family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Lipid Metabolism - glycerolipid; Phospholipase; Secreted; EC 3.1.1.3; Secreted, signal peptide Chromosomal Location of Human Ortholog: 18q21.1 Cellular Component: Golgi apparatus; extracellular space; cell surface; early endosome Molecular Function:heparin binding; lipoprotein lipase activity; phospholipase A1 activity; phospholipase activity Biological Process: cell proliferation; cholesterol homeostasis; reverse cholesterol transport; phospholipid catabolic process; regulation of lipoprotein metabolic process; lipid metabolic process; positive regulation of cholesterol transport; response to nutrient; phospholipid homeostasis |
| NCBI Summary: | The protein encoded by this gene has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. This protein is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9Y5X9 |
| NCBI GenInfo Identifier: | 22001808 |
| NCBI Gene ID: | 9388 |
| NCBI Accession: | Q9Y5X9.1 |
| UniProt Secondary Accession: | Q9Y5X9,Q6P9C8, Q6UW82, B0LPG6, |
| UniProt Related Accession: | Q9Y5X9 |
| Molecular Weight: | 500 |
| NCBI Full Name: | Endothelial lipase |
| NCBI Synonym Full Names: | lipase, endothelial |
| NCBI Official Symbol: | LIPG |
| NCBI Official Synonym Symbols: | EL; EDL; PRO719 |
| NCBI Protein Information: | endothelial lipase; lipoprotein lipase H; endothelial cell-derived lipase |
| UniProt Protein Name: | Endothelial lipase |
| UniProt Synonym Protein Names: | Endothelial cell-derived lipase; EDL; EL |
| Protein Family: | Endothelial lipase |
| UniProt Gene Name: | LIPG |
| UniProt Entry Name: | LIPE_HUMAN |
 | Western blot analysis of extracts of various cell lines, using LIPG antibody (CAB1891) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded rat kidney using LIPG antibody (CAB1891) at dilution of 1:200 (40x lens). |
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Rat LIPG / Endothelial Lipase ELISA Kit
Human LIPG / Endothelial Lipase ELISA Kit
