Anti-Lambda Light chain Antibody (CAB19831)

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SKU:
CAB19831
Product type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
IGLV151
V1-19
Frequently bought together:

Description

Product Name:Lambda Light chain Rabbit mAb
Product Code:CAB19831
Size:20uL, 50uL, 100uL
Synonyms:IGLV151, V1-19
Applications:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human Lambda Light chain
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:Mouse spleen, Rat spleen
Immunogen:A synthesized peptide derived from human Lambda Light chain
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:28820
Uniprot:P01701/P01842
Calculated MW:25kDa
Observed MW:25KDa
UniProt Protein Function:IGLV1-51: V segment of the variable region of immunoglobulins light chain that participates to the antigen recognition. Immunoglobulins (Igs), also known as antibodies, are membrane- bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound Igs serve as receptors which, upon binding of a specific antigen (Ag), trigger the clonal expansion and differentiation of B lymphocytes into Ig-secreting plasma cells. Secreted Igs mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable region of one heavy chain, together with that of its associated light chain. Thus, each Ig has two antigen binding sites with remarkable affinity for a particular antigen. The variable regions are assembled by a process called V(D)J recombination and can then be subjected to somatic hypermutation after exposure to antigen to allow affinity maturation for a particular Ag (PubMed:20176268, PubMed:17576170). {ECO:0000303|PubMed:17576170, ECO:0000303|PubMed:20176268, ECO:0000303|PubMed:22158414}. Immunoglobulins are composed of two identical heavy chains and two identical light chains, linked by disulfide bonds. {ECO:0000303|PubMed:20176268}
UniProt Protein Details:
NCBI Summary:
UniProt Code:P01701
NCBI GenInfo Identifier:126541
NCBI Gene ID:3535
NCBI Accession:P01701.1
UniProt Secondary Accession:P01701,P0CG04
UniProt Related Accession:P01701
Molecular Weight:~22.5kDa
NCBI Full Name:Ig lambda chain V-I region NEW
NCBI Synonym Full Names:
NCBI Official Symbol:
NCBI Official Synonym Symbols:
NCBI Protein Information:
UniProt Protein Name:Ig lambda chain V-I region NEW
UniProt Synonym Protein Names:
Protein Family:
UniProt Gene Name:
UniProt Entry Name:LV103_HUMAN

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