Anti-KLF4 Antibody (CAB18088)[KO Validated]
- SKU:
- CAB18088
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Antibody Name: | Anti-KLF4 Antibody [KO Validated] |
Antibody SKU: | CAB18088 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB IHC |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-479 of human KLF4 (NP_004226.3). |
Application: | WB IHC |
Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | HeLa |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-479 of human KLF4 (NP_004226.3). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | PPTA PFNL ADIN DVSP SGGF VAEL LRPE LDPV YIPP QQPQ PPGG GLMG KFVL KASL SAPG SEYG SPSV ISVS KGSP DGSH PVVV APYN GGPP RTCP KIKQ EAVS SCTH LGAG PPLS NGHR PAAH DFPL GRQL PSRT TPTL GLEE VLSS RDCH PALP LPPG FHPH PGPN YPSF LPDQ MQPQ VPPL HYQE LMPP GSCM PEEP KPKR GRRS WPRK RTAT HTCD YAGC GKTY TKSS HLKA HLRT HTGE KPYH CDWD GCGW KFAR SDEL TRHY RKHT GHRP FQCQ KCDR AFSR SDHL ALHM KRHF |
Gene ID: | 9314 |
Uniprot: | O43474 |
Cellular Location: | Nucleus |
Calculated MW: | 6kDa/12kDa/45kDa/51kDa/54kDa |
Observed MW: | 62kDa |
Synonyms: | EZF, GKLF, KLF4 |
Background: | This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms. |
UniProt Code: | O43474 |
NCBI GenInfo Identifier: | 194248077 |
NCBI Gene ID: | 9314 |
NCBI Accession: | NP_004226.3 |
UniProt Secondary Accession: | O43474,P78338, Q5T3J8, Q5T3J9, Q8N717, Q9UNP3, B2R8S4 B3KT79, L0R3I6, L0R4N5, |
UniProt Related Accession: | O43474 |
Molecular Weight: | 51kDa |
NCBI Full Name: | Krueppel-like factor 4 |
NCBI Synonym Full Names: | Kruppel-like factor 4 (gut) |
NCBI Official Symbol: | KLF4 |
NCBI Official Synonym Symbols: | EZF; GKLF |
NCBI Protein Information: | Krueppel-like factor 4; gut-enriched krueppel-like factor; epithelial zinc finger protein EZF; endothelial Kruppel-like zinc finger protein |
UniProt Protein Name: | Krueppel-like factor 4 |
UniProt Synonym Protein Names: | Epithelial zinc finger protein EZF; Gut-enriched krueppel-like factor |
Protein Family: | Krueppel-like factor |
UniProt Gene Name: | KLF4 |
UniProt Entry Name: | KLF4_HUMAN |