Anti-KIF20B Antibody (CAB15360)
- SKU:
- CAB15360
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| Antibody Name: | Anti-KIF20B Antibody |
| Antibody SKU: | CAB15360 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1200-1500 of human KIF20B (NP_057279.2). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:200 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | U-251MG, OVCAR3, 293T, HT-29, NIH/3T3, Mouse brain, Rat brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1200-1500 of human KIF20B (NP_057279.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | KHLL QLKE EEEE TNRQ ETEK LKEE LSAS SART QNLK ADLQ RKEE DYAD LKEK LTDA KKQI KQVQ KEVS VMRD EDKL LRIK INEL EKKK NQCS QELD MKQR TIQQ LKEQ LNNQ KVEE AIQQ YERA CKDL NVKE KIIE DMRM TLEE QEQT QVEQ DQVL EAKL EEVE RLAT ELEK WKEK CNDL ETKN NQRS NKEH ENNT DVLG KLTN LQDE LQES EQKY NADR KKWL EEKM MLIT QAKE AENI RNKE MKKY AEDR ERFF KQQN EMEI LTAQ LTEK DSDL QKWR EERD QLVA ALEI QLKA LISS N |
| Gene ID: | 9585 |
| Uniprot: | Q96Q89 |
| Cellular Location: | Cell projection, Cytoplasm, Midbody, Nucleus, axon, centrosome, cytoskeleton, growth cone, microtubule organizing center, nucleolus, nucleoplasm, spindle, spindle pole |
| Calculated MW: | 59kDa/199kDa/206kDa/210kDa/214kDa |
| Observed MW: | 210kDa |
| Synonyms: | KIF20B, CT90, KRMP1, MPHOSPH1, MPP-1, MPP1 |
| Background: |
| UniProt Protein Function: | Plus-end-directed motor enzyme that is required for completion of cytokinesis (PubMed:11470801, PubMed:12740395). Required for proper midbody organization and abscission in polarized cortical stem cells. Plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. Participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in cerebral cortex growth. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression (PubMed:17409436). |
| UniProt Code: | Q96Q89 |
| NCBI GenInfo Identifier: | 546231677 |
| NCBI Gene ID: | 9585 |
| NCBI Accession: | NP_001271188.1 |
| UniProt Secondary Accession: | Q96Q89,O43277, Q09471, Q2KQ73, Q32NE1, Q561V3, Q58EX8 Q5T9M8, Q5T9M9, Q5T9N0, Q5T9N1, A8MXM7, |
| UniProt Related Accession: | Q96Q89 |
| Molecular Weight: | 59,621 Da |
| NCBI Full Name: | kinesin-like protein KIF20B isoform 1 |
| NCBI Synonym Full Names: | kinesin family member 20B |
| NCBI Official Symbol: | KIF20B |
| NCBI Official Synonym Symbols: | CT90; MPP1; KRMP1; MPP-1; MPHOSPH1 |
| NCBI Protein Information: | kinesin-like protein KIF20B |
| UniProt Protein Name: | Kinesin-like protein KIF20B |
| UniProt Synonym Protein Names: | Cancer/testis antigen 90; CT90; Kinesin family member 20B |
| Protein Family: | Mitochondrial-processing peptidase |
| UniProt Gene Name: | KIF20B |
 | Western blot analysis of extracts of various cell lines, using KIF20B antibody (CAB15360) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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