Anti-K Cadherin Antibody (CAB4689)
- SKU:
- CAB4689
- Product type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Antibody Name: | Anti-K Cadherin Antibody |
Antibody SKU: | CAB4689 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | A synthesized peptide derived from human K Cadherin |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: | 293T, HepG2, Mouse brain, Rat brain |
Immunogen: | A synthesized peptide derived from human K Cadherin |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | Email for sequence |
Gene ID: | 1004 |
Uniprot: | P55285 |
Cellular Location: | |
Calculated MW: | 130kDa |
Observed MW: | 130KDa |
Synonyms: | CAD6, KCAD |
Background: | This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis. [provided by RefSeq, May 2011] |
UniProt Protein Function: | CDH6: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Cell adhesion Chromosomal Location of Human Ortholog: 5p13.3 Cellular Component: plasma membrane; integral to membrane Molecular Function:calcium ion binding Biological Process: intercellular junction assembly and maintenance; homophilic cell adhesion; cell adhesion |
NCBI Summary: | This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis. [provided by RefSeq, May 2011] |
UniProt Code: | P55285 |
NCBI GenInfo Identifier: | 1705545 |
NCBI Gene ID: | 1004 |
NCBI Accession: | P55285.1 |
UniProt Secondary Accession: | P55285,Q9BWS0, A8K5H5, |
UniProt Related Accession: | P55285 |
Molecular Weight: | 73,864 Da |
NCBI Full Name: | Cadherin-6 |
NCBI Synonym Full Names: | cadherin 6, type 2, K-cadherin (fetal kidney) |
NCBI Official Symbol: | CDH6 |
NCBI Official Synonym Symbols: | CAD6; KCAD |
NCBI Protein Information: | cadherin-6 |
UniProt Protein Name: | Cadherin-6 |
UniProt Synonym Protein Names: | Kidney cadherin; K-cadherin |
Protein Family: | Cadherin |
UniProt Gene Name: | CDH6 |
UniProt Entry Name: | CADH6_HUMAN |