Anti-IVNS1ABP Antibody (CAB4442)

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SKU:
CAB4442
Product type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
IVNS1ABP
FLARA3
HSPC068
KLHL39
ND1
NS-1
NS1-BP
NS1BP
Frequently bought together:

Description

Product Name:IVNS1ABP Rabbit pAb
Product Code:CAB4442
Size:20uL, 50uL, 100uL
Synonyms:IVNS1ABP, FLARA3, HSPC068, KLHL39, ND1, NS-1, NS1-BP, NS1BP
Applications:WB, IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human IVNS1ABP (NP_006460.2).
Applications:WB, IHC
Recommended Dilutions:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:HT-29, Mouse kidney, Mouse lung, Rat spleen
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human IVNS1ABP (NP_006460.2).
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MIPN GYLM FEDE NFIE SSVA KLNA LRKS GQFC DVRL QVCG HEML AHRA VLAC CSPY LFEI FNSD SDPH GISH VKFD DLNP EAVE VLLN YAYT AQLK ADKE LVKD VYSA AKKL KMDR VKQV CGDY LLSR MDVT SCIS YRNF ASCM GDSR LLNK VDAY IQEH LLQI SEEE EFLK LPRL KLEV MLED NVCL PSNG KLYT KVIN WVQR SIWE NGDS LEEL MEEV QTLY YSAD HKLL DGNL LDGQ AEVF GSDD DHIQ FVQK KPPR ENGH KQIS SSST GCLS SPNA TVQS PKHE WKIV ASEK TSNN
Gene ID:10625
Uniprot:Q9Y6Y0
Cellular Location:Cytoplasm, Nucleus, cytoskeleton, nucleoplasm
Calculated MW:71kDa
Observed MW:72kDa
UniProt Protein Function:IVNS1ABP: Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines. May be a component of the cellular splicing machinery with a role in pre-mRNA splicing; may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription.
UniProt Protein Details:

Chromosomal Location of Human Ortholog: 1q25.1-q31.1

Cellular Component: nucleoplasm; spliceosome; transcription factor complex; cytoplasm; actin cytoskeleton

Biological Process: transcription from RNA polymerase III promoter; viral reproduction; response to virus; RNA splicing

UniProt Code:Q9Y6Y0
NCBI GenInfo Identifier:146325015
NCBI Gene ID:10625
NCBI Accession:Q9Y6Y0.3
UniProt Secondary Accession:Q9Y6Y0,Q1G4T6, Q1G4T7, Q5TF75, Q6NW38, Q7LCG2, Q9NZX0 Q9Y480, A8K8R6,
UniProt Related Accession:Q9Y6Y0
Molecular Weight:642
NCBI Full Name:Influenza virus NS1A-binding protein
NCBI Synonym Full Names:influenza virus NS1A binding protein
NCBI Official Symbol:IVNS1ABP  
NCBI Official Synonym Symbols:ND1; NS-1; NS1BP; FLARA3; KLHL39; NS1-BP; HSPC068  
NCBI Protein Information:influenza virus NS1A-binding protein; NS1-binding protein; NCX downstream gene 1; kelch-like family member 39; aryl hydrocarbon receptor-associated 3; aryl hydrocarbon receptor-associated protein 3
UniProt Protein Name:Influenza virus NS1A-binding protein
UniProt Synonym Protein Names:Aryl hydrocarbon receptor-associated protein 3
Protein Family:Influenza virus NS1A-binding protein
UniProt Gene Name:IVNS1ABP  
UniProt Entry Name:NS1BP_HUMAN

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