Anti-ITGA11 Antibody (CAB10084)
- SKU:
- CAB10084
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Antibody Name: | Anti-ITGA11 Antibody |
| Antibody SKU: | CAB10084 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 940-1141 of human ITGA11 (NP_001004439.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | HeLa, SH-SY5Y |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 940-1141 of human ITGA11 (NP_001004439.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | KEDN VAPL RFHL KYEA DVLF TRSS SLSH YEVK PNSS LERY DGIG PPFS CIFR IQNL GLFP IHGM MMKI TIPI ATRS GNRL LKLR DFLT DEAN TSCN IWGN STEY RPTP VEED LRRA PQLN HSNS DVVS INCN IRLV PNQE INFH LLGN LWLR SLKA LKYK SMKI MVNA ALQR QFHS PFIF REED PSRQ IVFE ISKQ EDWQ VP |
| Gene ID: | 22801 |
| Uniprot: | Q9UKX5 |
| Cellular Location: | Membrane, Single-pass type I membrane protein |
| Calculated MW: | 133kDa |
| Observed MW: | 160kDa |
| Synonyms: | ITGA11, HsT18964 |
| Background: | This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears to bind collagen in this form. Therefore, the protein may be involved in attaching muscle tissue to the extracellular matrix. Alternative transcriptional splice variants have been found for this gene, but their biological validity is not determined. |
| UniProt Protein Function: | Integrin alpha-11/beta-1 is a receptor for collagen. |
| NCBI Summary: | This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears to bind collagen in this form. Therefore, the protein may be involved in attaching muscle tissue to the extracellular matrix. Alternative transcriptional splice variants have been found for this gene, but their biological validity is not determined. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9UKX5 |
| NCBI GenInfo Identifier: | 52485853 |
| NCBI Gene ID: | 22801 |
| NCBI Accession: | NP_001004439.1 |
| UniProt Secondary Accession: | Q9UKX5,Q8WYI8, Q9UKQ1, J3KQM2, |
| UniProt Related Accession: | Q9UKX5 |
| Molecular Weight: | 130 |
| NCBI Full Name: | integrin alpha-11 |
| NCBI Synonym Full Names: | integrin subunit alpha 11 |
| NCBI Official Symbol: | ITGA11 |
| NCBI Official Synonym Symbols: | HsT18964 |
| NCBI Protein Information: | integrin alpha-11 |
| UniProt Protein Name: | Integrin alpha-11 |
| UniProt Gene Name: | ITGA11 |
 | Western blot analysis of extracts of various cell lines, using ITGA11 antibody (CAB10084) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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